Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 11/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12598566 | 0.81 | AR (0.63) | AR | |
| SCHEMBL13439584 | 0.68 | AR (0.58) | ARHPGD | |
| SCHEMBL13439586 | 0.65 | AR (0.44) | ARKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL1771212 | 0.64 | AR (1.00) | AR | |
| SCHEMBL3989160 | 0.63 | KMT2A (1.00) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL1772814 | 0.61 | AR (0.70) | AR | |
| SCHEMBL1771660 | 0.61 | AR (0.71) | ARALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL2272356 | 0.59 | AR (0.62) | ARALDH1A1KDM4EHPGDUSP2 | |
| SCHEMBL21525863 | 0.58 | AR (0.47) | ARALDH1A1HPGDTSHR | |
| SCHEMBL28219703 | 0.58 | ALDH1A1 (0.50) | ARKMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696246-B2 | Bicyclic androgen and progesterone receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-04-13 | — | — | US | disclosed |