Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 15/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13439584 | 0.80 | AR (0.58) | ARLMNAHPGD | |
| SCHEMBL4148535 | 0.76 | AR (0.48) | ARMEN1KMT2ALMNAKDM4E | |
| SCHEMBL1771947 | 0.76 | AR (0.68) | AR | |
| SCHEMBL12649315 | 0.70 | AR (0.58) | ARMEN1KMT2AGAAHPGD | |
| SCHEMBL13439804 | 0.67 | AR (0.70) | ARMEN1KMT2AGAA | |
| SCHEMBL13439631 | 0.67 | AR (0.56) | ARMEN1KMT2AGAA | |
| SCHEMBL13439806 | 0.65 | AR (0.69) | ARMEN1KMT2AGAA | |
| SCHEMBL11857777 | 0.65 | KIF11 (0.51) | ARLMNA | |
| SCHEMBL1770840 | 0.65 | AR (0.55) | ARGAALMNAHPGDALDH1A1 | |
| SCHEMBL13439585 | 0.65 | AR (0.47) | ARMEN1KMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696246-B2 | Bicyclic androgen and progesterone receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-04-13 | — | — | US | disclosed |