Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11929796 | 0.91 | MEN1 (0.43) | AKT1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL11929768 | 0.91 | MAPT (0.40) | AKT1BRAFMAPTRAB9AHTT | |
| SCHEMBL13813998 | 0.91 | LMNA (0.47) | AKT1BRAFMAPTRAB9AHTT | |
| SCHEMBL11926394 | 0.88 | AKT1 (0.50) | AKT1EPHX2BRAFMAPTRAB9A | |
| SCHEMBL429028 | 0.86 | EPHX2 (0.56) | AKT1EPHX2BRAFMAPTRAB9A | |
| SCHEMBL11929767 | 0.85 | MAPK14 (0.43) | BRAFRAF1HTR1BMAPK14 | |
| SCHEMBL11929361 | 0.85 | RAF1 (0.40) | BRAFMAPTHTTRAF1MEN1 | |
| SCHEMBL13439833 | 0.81 | MAPT (0.35) | MAPTHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11926397 | 0.81 | EPHX2 (0.47) | AKT1EPHX2BRAFCASRTP53 | |
| SCHEMBL11926393 | 0.80 | EPHX2 (0.47) | AKT1EPHX2BRAFCASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696202-B2 | IL-12 modulatory compounds | SYNTA PHARMACEUTICALS CORP. (US) | 2010-04-13 | — | — | US | disclosed |