Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11926379 | 0.83 | AKT1 (0.41) | MAPTKMT2AMAPK1HTTMTOR | |
| SCHEMBL11929768 | 0.82 | MAPT (0.40) | MAPTMEN1KMT2APKMMAPK1 | |
| SCHEMBL11929796 | 0.82 | MEN1 (0.43) | MAPTMEN1KMT2AMAPK1NAPEPLD | |
| SCHEMBL13813998 | 0.81 | LMNA (0.47) | MAPTMEN1KMT2APKMMAPK1 | |
| SCHEMBL13439731 | 0.81 | AKT1 (0.46) | MAPTMEN1KMT2APKMMAPK1 | |
| SCHEMBL11929767 | 0.80 | MAPK14 (0.43) | — | |
| SCHEMBL11929361 | 0.80 | RAF1 (0.40) | MAPTMEN1KMT2APKMMAPK1 | |
| SCHEMBL11930625 | 0.78 | MEN1 (0.40) | MAPTMEN1KMT2APKMMAPK1 | |
| SCHEMBL13813988 | 0.75 | AKT1 (0.42) | MAPTMEN1KMT2AHTTNAPEPLD | |
| SCHEMBL16844680 | 0.68 | MAPT (0.38) | MAPTMEN1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696202-B2 | IL-12 modulatory compounds | SYNTA PHARMACEUTICALS CORP. (US) | 2010-04-13 | — | — | US | disclosed |