Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPEPLD | Q6IQ20 | 18/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13439916 | 0.84 | MAPT (0.40) | KDM4EALDH1A1CYP3A4GAAHPGD | |
| SCHEMBL13439938 | 0.83 | MAPT (0.43) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL13439939 | 0.81 | GRM4 (0.43) | — | |
| SCHEMBL11926309 | 0.81 | AKT1 (0.54) | NAPEPLDKDM4EALDH1A1CYP3A4RAB9A | |
| SCHEMBL13439936 | 0.80 | IRAK4 (0.48) | KDM4EALDH1A1GBA1 | |
| SCHEMBL11926308 | 0.79 | KDM4E (0.43) | NAPEPLDKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL13439743 | 0.79 | RAF1 (0.42) | KDM4EALDH1A1GLAHPGDRAB9A | |
| SCHEMBL13439915 | 0.78 | MAPT (0.40) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL13439917 | 0.77 | DGAT1 (0.47) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL3102407 | 0.76 | PIK3CA (0.53) | NAPEPLD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696202-B2 | IL-12 modulatory compounds | SYNTA PHARMACEUTICALS CORP. (US) | 2010-04-13 | — | — | US | disclosed |