Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 3/20 | 0.79 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.79 |
| ▸ | MAOA | P21397 | 2/20 | 0.79 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.79 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.79 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.79 |
| ▸ | HTR2C | P28335 | 1/20 | 0.79 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.79 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.53 |
| ▸ | SCN1A | P35498 | 3/20 | 0.53 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.53 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13440000 | 0.89 | HTR3A (0.70) | HTR3ACHRM2MAOAHRH3KCNH2 | |
| Chloroprocaine SCHEMBL6676 | 0.88 | HRH3 (1.00) | HTR3ACHRM2MAOAHRH3KCNH2 | |
| Chloroprocaine SCHEMBL29354179 | 0.88 | HRH3 (1.00) | HTR3ACHRM2MAOAHRH3KCNH2 | |
| Chloroprocaine SCHEMBL1650786 | 0.87 | HRH3 (0.97) | HTR3ACHRM2MAOAHRH3KCNH2 | |
| Chloroprocaine SCHEMBL21612249 | 0.87 | HRH3 (0.97) | HTR3ACHRM2MAOAHRH3KCNH2 | |
| Chloroprocaine SCHEMBL24096 | 0.87 | HRH3 (0.97) | HTR3ACHRM2MAOAHRH3KCNH2 | |
| SCHEMBL13440002 | 0.84 | HTR3A (0.70) | HTR3ACHRM2MAOAHRH3KCNH2 | |
| SCHEMBL13439998 | 0.84 | HTR3A (0.73) | HTR3ACHRM2MAOAHRH3KCNH2 | |
| Chloroprocaine SCHEMBL28104711 | 0.83 | HRH3 (0.88) | HTR3ACHRM2MAOAHRH3KCNH2 | |
| SCHEMBL13440006 | 0.83 | HRH3 (0.84) | HTR3ACHRM2MAOAHRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056575-A1 | Anesthetic Compounds | SIGNATURE THERAPEUTICS, INC. | 2010-03-04 | — | — | US | disclosed |
| US-20100056575-A1 | Anesthetic Compounds | SIGNATURE THERAPEUTICS, INC. | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056575-A1 | Anesthetic Compounds | OPRL1, OPRM1, CYP3A5 | HTR3A 547/4885CHRM2 628/4885MAOA 658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.