Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 20/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.50 |
| ▸ | CCR5 | P51681 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3028334 | 0.88 | CCR2 (0.53) | CCR2KCNH2CCR5 | |
| SCHEMBL3326136 | 0.87 | CCR2 (0.56) | CCR2KCNH2CCR5 | |
| SCHEMBL3330419 | 0.87 | CCR2 (0.56) | CCR2KCNH2CCR5 | |
| SCHEMBL13335000 | 0.82 | CCR2 (0.53) | CCR2KCNH2CCR5 | |
| SCHEMBL13335001 | 0.81 | CCR2 (0.53) | CCR2KCNH2CCR5 | |
| Hydrochloric Acid SCHEMBL3327119 | 0.81 | CCR2 (0.52) | CCR2KCNH2CCR5 | |
| Hydrochloric Acid SCHEMBL3327112 | 0.81 | CCR2 (0.52) | CCR2KCNH2CCR5 | |
| SCHEMBL4154279 | 0.79 | CCR2 (0.50) | CCR2KCNH2CCR5 | |
| SCHEMBL3324428 | 0.79 | CCR2 (0.66) | CCR2KCNH2CCR5 | |
| SCHEMBL3324424 | 0.79 | CCR2 (0.66) | CCR2KCNH2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700624-B2 | 3-aminocyclopentanecrboxamides as modulators of chemokine receptors | INCYTE CORPORATION (US) | 2010-04-20 | — | — | US | disclosed |
| US-20070149532-A1 | 3-Aminocyclopentanecarboxamides as Modulators of Chemokine Receptors | INCYTE CORPORATION | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149532-A1 | 3-Aminocyclopentanecarboxamides as Modulators of Chemokine Receptors | CCR5, CCR2, ACKR3 | CCR2 2/4885KCNH2 3609/4885CCR5 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.