⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11622731 | 0.65 | MEN1 (0.40) | — | |
| SCHEMBL30600357 | 0.64 | GAA (0.36) | — | |
| SCHEMBL9935222 | 0.62 | — | — | |
| SCHEMBL11884871 | 0.62 | LMNA (0.34) | — | |
| SCHEMBL496558 | 0.62 | — | — | |
| SCHEMBL38532 | 0.62 | — | — | |
| SCHEMBL1272340 | 0.61 | — | — | |
| SCHEMBL240371 | 0.61 | MAPT (0.43) | — | |
| SCHEMBL13819803 | 0.61 | MAPT (0.43) | — | |
| SCHEMBL21170617 | 0.61 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3788 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290776-A | Preparation method of conjugated polymer nanoparticles with ultra-small particle size | 中国科学院化学研究所 | 2024-07-05 | — | — | CN | claimed |
| US-12018030-B2 | Pyrrolo and pyrazolopyrimidines as ubiquitin-specific protease 7 inhibitors | VALO HEALTH, INC. (US) | 2024-06-25 | — | — | US | claimed |
| US-11987588-B2 | Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2024-05-21 | — | — | US | claimed |
| US-20240051985-A1 | METTL3 MODULATORS | ACCENT THERAPEUTICS INC (US) | 2024-02-15 | — | — | US | claimed |
| EP-4295910-A2 | METHODS FOR TREATING MULTIPLE SCLEROSIS USING PYRIMIDINE AND PYRIDINE COMPOUNDS WITH BTK INHIBITORY ACTIVITY | Merck Patent GmbH (DE) | 2023-12-27 | — | — | EP | claimed |
| US-11739071-B2 | Quinazolinones and azaquinazolinones as ubiquitin-specific protease 7 inhibitors | VALO HEALTH, INC. (US) | 2023-08-29 | — | — | US | claimed |
| EP-4229067-A1 | METTL3 MODULATORS | Accent Therapeutics, Inc. (US) | 2023-08-23 | — | — | EP | claimed |
| WO-2023150526-A1 | COMPETITIVE AND NONCOMPETITIVE OCTAHYDROCYCLOPENTA[C]PYRROLE INHIBITORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M5 | VANDERBILT UNIVERSITY (US) | 2023-08-10 | — | — | WO | claimed |
| EP-3720858-B1 | MODULATORS OF THE BETA-3 ADRENERGIC RECEPTOR USEFUL FOR THE TREATMENT OR PREVENTION OF HEART FAILURE AND DISORDERS RELATED THERETO | ARENA PHARM INC (US) | 2023-06-07 | — | — | EP | claimed |
| US-20230157996-A1 | SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD AND USE THEREOF | Shenzhen Bay Laboratory (CN) | 2023-05-25 | — | — | US | claimed |
| US-4879384-A | CYCLIC THIAALKANONE DIOXIDE AND UNSATURATED AMINE ESTER | ORTHO PHARMACEUTICAL CORPORATION (US) | 1989-11-07 | — | — | US | claimed |
| US-4845225-A | CARDIOVASCULAR, ANTIASTHMATIC AND ANTIBRONCHOCONSTRICTOR AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1989-07-04 | — | — | US | claimed |
| US-4777167-A | CALCIUM CHANNEL ANTAGONIST, ANTICOAGULANTS, ANTIASTHMATIC, BRONCHODILATOR AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1988-10-11 | — | — | US | claimed |
| US-4705785-A | Substituted thiacycloalkeno (3,2-b) pyridines and pharmaceutical compositions and method of use | ORTHO PHARMACEUTICAL CORPORATION (US) | 1987-11-10 | — | — | US | claimed |
| EP-0241281-A2 | Substituted thiacycloalkeno [3,2-b] pyridines, methods of preparation, compositions and method of use | ORTHO PHARMACEUTICAL CORPORATION (US) | 1987-10-14 | — | — | EP | claimed |
| EP-0222702-A2 | Basic carbonyl derivatives | CIBA-GEIGY AG (CH) | 1987-05-20 | — | — | EP | claimed |
| EP-0214094-A1 | 1,4-Dihydropyridine derivatives | CIBA-GEIGY AG (CH) | 1987-03-11 | — | — | EP | claimed |
| EP-0174654-A2 | Carbonyl derivatives | CIBA-GEIGY AG (CH) | 1986-03-19 | — | — | EP | claimed |
| EP-0174653-A2 | Phenylalkyl derivatives | CIBA-GEIGY AG (CH) | 1986-03-19 | — | — | EP | claimed |
| US-4113867-A | ANTHELMINTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1978-09-12 | — | — | US | claimed |