Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYLK4 | Q86YV6 | 2/20 | 0.36 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.34 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 3/20 | 0.33 |
| ▸ | CDC7 | O00311 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.32 |
| ▸ | FEN1 | P39748 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13408194 | 0.91 | TBK1 (0.41) | MYLK4STK17APIK3CAPIK3CDPIK3R1 | |
| SCHEMBL13442301 | 0.91 | MAPT (0.38) | MYLK4STK17AMAPTMAPKAPK2TBK1 | |
| SCHEMBL13442018 | 0.91 | MAPT (0.38) | MYLK4STK17AMAPTMAPKAPK2TBK1 | |
| SCHEMBL13441991 | 0.88 | MAPKAPK2 (0.34) | PIK3CAPIK3CDPIK3R1PIK3CBMAPT | |
| SCHEMBL13408186 | 0.87 | CDC7 (0.43) | MYLK4STK17APIK3CAPIK3CDPIK3R1 | |
| SCHEMBL14283774 | 0.86 | PIK3CA (0.41) | MYLK4STK17APIK3CAPIK3CDPIK3R1 | |
| Trifluoroacetic Acid SCHEMBL3613213 | 0.84 | TBK1 (0.36) | MAPTTBK1PIM1CDC7CDK9 | |
| SCHEMBL13442621 | 0.82 | LRRK2 (0.33) | PIK3CAPIK3CDPIK3CBMAPTMAPKAPK2 | |
| SCHEMBL13408196 | 0.82 | PIM1 (0.43) | MYLK4STK17AMAPTMAPKAPK2TBK1 | |
| SCHEMBL13408197 | 0.82 | PIM1 (0.42) | MYLK4STK17AMAPTMAPKAPK2PRKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105664-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105664-A1 | ORGANIC COMPOUNDS | SLCO1B3, SLCO1B1, SLC10A6 | MYLK4 4592/4885STK17A 3404/4885PIK3CA 1285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.