Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 9/20 | 0.39 |
| ▸ | DRD2 | P14416 | 8/20 | 0.39 |
| ▸ | DRD1 | P21728 | 8/20 | 0.39 |
| ▸ | DRD4 | P21917 | 6/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | HTR2B | P41595 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12723261 | 0.83 | MAOA (0.45) | DRD3DRD2DRD1DRD4HTR2A | |
| SCHEMBL29351597 | 0.82 | MAOA (0.52) | DRD3DRD2DRD1DRD4HTR2A | |
| SCHEMBL975897 | 0.82 | MAOA (0.52) | DRD3DRD2DRD1DRD4HTR2A | |
| Bromide SCHEMBL27751559 | 0.80 | MAOA (0.50) | DRD3DRD2DRD1DRD4HTR2A | |
| SCHEMBL29735917 | 0.80 | MAOA (0.50) | DRD3DRD2DRD1DRD4HTR2A | |
| Iodide SCHEMBL11862710 | 0.80 | MAOA (0.50) | DRD3DRD2DRD1DRD4HTR2A | |
| SCHEMBL12841616 | 0.80 | HTR2A (0.45) | DRD3DRD2DRD1DRD4HTR2A | |
| SCHEMBL17423265 | 0.79 | ADRA2A (0.51) | DRD3DRD2DRD1DRD4HTR2A | |
| SCHEMBL2096899 | 0.79 | DRD1 (0.54) | DRD3DRD2DRD1DRD4HTR2A | |
| SCHEMBL16852144 | 0.79 | MEN1 (0.41) | DRD3DRD2DRD1DRD4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161319-A2 | Benzo(c)phenanthrene derivatives and organic electroluminescent device using the same | Gracel Display Inc. (KR) | 2010-03-10 | — | — | EP | disclosed |