Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 8/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47007 | 0.82 | KDM4E (0.55) | KDM4EALDH1A1P2RX4SMN1; SMN2GAA | |
| SCHEMBL31067286 | 0.82 | KDM4E (0.55) | KDM4EALDH1A1P2RX4SMN1; SMN2GAA | |
| Hydrogen Sulfide SCHEMBL28845788 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1P2RX4SMN1; SMN2GAA | |
| SCHEMBL12841614 | 0.80 | KDM4E (0.47) | KDM4EALDH1A1P2RX4SMN1; SMN2GAA | |
| SCHEMBL21497997 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1P2RX4SMN1; SMN2GAA | |
| SCHEMBL26840780 | 0.79 | MEN1 (0.47) | KDM4EALDH1A1P2RX4SMN1; SMN2GAA | |
| SCHEMBL16810785 | 0.77 | KDM4E (0.45) | KDM4EALDH1A1P2RX4SMN1; SMN2GAA | |
| SCHEMBL13706555 | 0.77 | CASP3 (0.46) | KDM4EALDH1A1MAPTPIM1MEN1 | |
| SCHEMBL12776591 | 0.76 | SMN1; SMN2 (0.59) | KDM4EALDH1A1P2RX4SMN1; SMN2GAA | |
| SCHEMBL1102428 | 0.76 | KDM4E (0.44) | KDM4EALDH1A1P2RX4SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109329-A1 | TRICYCLIC COMPOUNDS AND RELATED COMPOSITIONS, ZINC ELECTROCHEMICAL CELLS, BATTERIES, METHODS AND SYSTEMS | ALIONYX ENERGY SYSTEMS (US) | 2022-05-27 | — | — | WO | disclosed |
| EP-2161319-A2 | Benzo(c)phenanthrene derivatives and organic electroluminescent device using the same | Gracel Display Inc. (KR) | 2010-03-10 | — | — | EP | disclosed |