SCHEMBL47007

SCHEMBL47007

CN1c2ccccc2Oc2ccccc21

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.55
ALDH1A1 P00352 2/20 0.55
P2RX4 Q99571 13/20 0.48
MAOA P21397 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.42
GLA P06280 1/20 0.42
GAA P10253 1/20 0.42
HPGD P15428 1/20 0.42
RAB9A P51151 1/20 0.42
P2RX1 P51575 1/20 0.42
MAPT P10636 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
SIGMAR1 Q99720 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31067286 1.00 KDM4E (0.55) KDM4EALDH1A1P2RX4MAOASMN1; SMN2
Hydrogen Sulfide SCHEMBL28845788 0.97 KDM4E (0.53) KDM4EALDH1A1P2RX4MAOASMN1; SMN2
Formic Acid SCHEMBL8502185 0.87 P2RX4 (0.49) KDM4EALDH1A1P2RX4SMN1; SMN2GAA
SCHEMBL12841614 0.84 KDM4E (0.47) KDM4EALDH1A1P2RX4SMN1; SMN2GLA
SCHEMBL12776591 0.84 SMN1; SMN2 (0.59) KDM4EALDH1A1P2RX4MAOASMN1; SMN2
SCHEMBL15183513 0.84 KDM4E (0.47) KDM4EALDH1A1P2RX4SMN1; SMN2GLA
SCHEMBL4012288 0.83 KDM4E (0.46) KDM4EALDH1A1P2RX4MAOASMN1; SMN2
SCHEMBL18637369 0.82 KDM4E (0.54) KDM4EALDH1A1P2RX4
SCHEMBL19417365 0.82 KDM4E (0.46) KDM4EALDH1A1P2RX4MAOASMN1; SMN2
SCHEMBL13445191 0.82 KDM4E (0.46) KDM4EALDH1A1P2RX4MAOASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1421 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113200936-B 10-methylphenoxazine derivative, zirconium metal organic framework material thereof and preparation method 南京工业大学 2022-10-21 CN claimed
CN-113200936-A 10-methylphenoxazine derivative, zirconium metal organic framework material thereof and preparation method 南京工业大学 2021-08-03 CN claimed
US-8012705-B2 Nonseparation assay methods BECKMAN COULTER, INC. (US) 2011-09-06 US claimed
US-20110183361-A1 Nonseparation Assay Methods BECKMAN COULTER, INC. (US) 2011-07-28 US claimed
US-7351395-B1 Catalytically saturating polycyclic aromatic hydrocarbons for storage, then dehydrogenation with catalyst to release hydrogen; supplying hydrogen to fuel cells AIR PRODUCTS AND CHEMICALS, INC. (US) 2008-04-01 US claimed
US-20070261806-A1 Treatment of Pulp Stocks Using Oxidative Enzymes to Reduce Pitch Deposition ENZYMATIC DEINKING TECHNOLOGIES, LLC 2007-11-15 US claimed
EP-0707637-B1 ENHANCEMENT OF LACCASE REACTIONS NOVOZYMES AS (DK) 2005-11-02 EP claimed
EP-1137391-B1 METHOD FOR TREATING HAIR NOVOZYMES AS (DK) 2004-11-03 EP claimed
US-20040049859-A1 Enzyme composition for bleaching human keratinous fibres and bleaching method L'OREAL S.A. (FR) 2004-03-18 US claimed
US-20040025265-A1 Enzyme composition for bleaching human keratinous fibres and bleaching method LANG GERARD (FR) 2004-02-12 US claimed
WO-1997031088-A1 COATED PEROXIDASE-CONTAINING PREPARATION, AND COMPOSITIONS COMPRISING SUCH A PREPARATION NOVO NORDISK A/S (DK) 1997-08-28 WO claimed
EP-0763094-A1 DYE-TRANSFER INHIBITORY PREPARATION, AND DETERGENT COMPOSITION COMPRISING SUCH A PREPARATION NOVO NORDISK A/S (DK) 1997-03-19 EP claimed
EP-0707637-A1 ENHANCEMENT OF LACCASE REACTIONS NOVO NORDISK A/S (DK) 1996-04-24 EP claimed
WO-1996006930-A1 COPRINACEAE LACCASES NOVO NORDISK A/S (DK) 1996-03-07 WO claimed
WO-1995033039-A1 DYE-TRANSFER INHIBITORY PREPARATION, AND DETERGENT COMPOSITION COMPRISING SUCH A PREPARATION NOVO NORDISK A/S (DK) 1995-12-07 WO claimed
EP-0679183-A1 ENHANCEMENT OF ENZYME REACTIONS NOVO NORDISK A/S (DK) 1995-11-02 EP claimed
WO-1995001426-A1 ENHANCEMENT OF LACCASE REACTIONS NOVO NORDISK A/S (DK) 1995-01-12 WO claimed
WO-1994012621-A1 ENHANCEMENT OF ENZYME REACTIONS NOVO NORDISK (DK) 1994-06-09 WO claimed
US-4616069-A REACTING THE ALKALI METAL OR ALKALINE EARTH METAL TERMINATED POLYMER WITH TIN COMPOUND AND ORGANIC COMPOUND HAVING AMIDE OR THIOAMIDE LINKAGES NIPPON ZEON CO., LTD. (JP) 1986-10-07 US claimed
US-4614771-A POLYMERIZATION WITH AROMATIC VINYL MONOMER AND ALKALINE(OR ALKALINE EARTH) METAL, THEN MINO(OR AMINOTHIO)ALDEHYDES OR KETONES NIPPON ZEON CO., LTD. (JP) 1986-09-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040025265-A1 Enzyme composition for bleaching human keratinous fibres and bleaching method KRT18, LPO, ALDH1A2 KDM4E 498/4885ALDH1A1 494/4885P2RX4 4155/4885
US-20040049859-A1 Enzyme composition for bleaching human keratinous fibres and bleaching method KRT18, COXFA4, LPO KDM4E 403/4885ALDH1A1 322/4885P2RX4 3353/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.