Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40405 | 0.88 | MAPT (0.41) | NPC1MAPTRAB9AVDRACLY | |
| SCHEMBL13169002 | 0.82 | MAPT (0.37) | NPC1MAPTRAB9AVDRACLY | |
| SCHEMBL17902936 | 0.81 | OXTR (0.40) | NPC1MAPTRAB9AVDRACLY | |
| SCHEMBL22332095 | 0.81 | TSHR (0.43) | NPC1MAPTRAB9A | |
| SCHEMBL803057 | 0.81 | MAPT (0.41) | NPC1MAPTRAB9AVDRACLY | |
| SCHEMBL17703322 | 0.81 | MAPT (0.41) | NPC1MAPTRAB9AVDRACLY | |
| SCHEMBL14694381 | 0.81 | MAPT (0.41) | NPC1MAPTRAB9AVDRACLY | |
| SCHEMBL10015232 | 0.78 | NPC1 (0.41) | NPC1MAPTRAB9AVDRACLY | |
| SCHEMBL19751522 | 0.78 | NPC1 (0.33) | NPC1MAPTRAB9AVDRACLY | |
| SCHEMBL15908156 | 0.77 | MAPT (0.40) | NPC1MAPTRAB9AVDRACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687570-B2 | Thermosetting resin material | AKEBONO BRAKE INDUSTRY CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |
| US-7687570-B2 | Thermosetting resin material | AKEBONO BRAKE INDUSTRY CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |
| US-20080319124-A1 | Thermosetting resin material | AKEBONO BRAKE INDUSTRY CO., LTD. | 2008-12-25 | — | — | US | disclosed |
| US-20080319124-A1 | Thermosetting resin material | AKEBONO BRAKE INDUSTRY CO., LTD. | 2008-12-25 | — | — | US | disclosed |