SCHEMBL40405

SCHEMBL40405

CC(C)(c1ccc2c(c1)CN(c1ccccc1)CO2)c1ccc2c(c1)CN(c1ccccc1)CO2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.41
NPC1 O15118 3/20 0.41
RAB9A P51151 2/20 0.41
VDR P11473 1/20 0.40
ACLY P53396 1/20 0.36
ALDH1A1 P00352 3/20 0.34
GAA P10253 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MAPK1 P28482 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TSHR P16473 2/20 0.33
CYP3A4 P08684 2/20 0.32
CYP2D6 P10635 1/20 0.32
HIF1A Q16665 1/20 0.32
LMNA P02545 2/20 0.31
CSNK2A2 P19784 1/20 0.31
CSNK2B P67870 1/20 0.31
CSNK2A1 P68400 1/20 0.31
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13169002 0.94 MAPT (0.37) MAPTNPC1RAB9AVDRACLY
SCHEMBL803057 0.91 MAPT (0.41) MAPTNPC1RAB9AVDRACLY
SCHEMBL17703322 0.91 MAPT (0.41) MAPTNPC1RAB9AVDRACLY
SCHEMBL14694381 0.91 MAPT (0.41) MAPTNPC1RAB9AVDRACLY
SCHEMBL17902936 0.89 OXTR (0.40) MAPTNPC1RAB9AVDRACLY
SCHEMBL10015232 0.89 NPC1 (0.41) MAPTNPC1RAB9AVDRACLY
SCHEMBL13445261 0.88 NPC1 (0.33) MAPTNPC1RAB9AVDRACLY
SCHEMBL19751522 0.88 NPC1 (0.33) MAPTNPC1RAB9AVDRACLY
SCHEMBL15908156 0.87 MAPT (0.40) MAPTNPC1RAB9AVDRACLY
SCHEMBL22590645 0.87 NPC1 (0.35) MAPTNPC1RAB9AVDRACLY

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116693236-B Energy-saving environment-friendly floating bead fireproof air duct board and preparation method thereof 山东万能空调设备有限公司 2023-10-03 CN claimed
CN-116693236-A Energy-saving environment-friendly floating bead fireproof air duct board and preparation method thereof 山东万能空调设备有限公司 2023-09-05 CN claimed
US-6905590-B2 Coating composition containing benzoxazine compound NIPPON PAINT CO., LTD. (JP) 2005-06-14 US claimed
US-20030038031-A1 Coating composition containing benzoxazine compound NIPPON PAINT CO., LTD. 2003-02-27 US claimed
EP-1247844-A2 Coating composition containing benzoxazine compounds Nippon Paint Co., Ltd. (JP) 2002-10-09 EP claimed
US-12018154-B2 Rubber composition offering high stiffness and low hysteresis THE GOODYEAR TIRE & RUBBER COMPANY (US) 2024-06-25 US disclosed
US-12018154-B2 Rubber composition offering high stiffness and low hysteresis THE GOODYEAR TIRE & RUBBER COMPANY (US) 2024-06-25 US disclosed
WO-2024101234-A1 BISMALEIMIDE AND PRODUCTION METHOD THEREFOR ユニチカ株式会社 2024-05-16 WO disclosed
CN-112673043-B Curing agent composition for epoxy resin mixtures, epoxy resin mixtures and multicomponent epoxy resin systems 喜利得股份公司 2024-03-29 CN disclosed
CN-117700990-A Resin composition, adhesive, coating agent, cured product, adhesive sheet, resin-coated copper foil, copper-clad laminate, and printed wiring board 荒川化学工业株式会社 2024-03-15 CN disclosed
CN-117624855-A Biodegradable packaging film and preparation method thereof 中国石油化工股份有限公司 2024-03-01 CN disclosed
US-20240026069-A1 POLYMER, COMPOSITION, CURED PRODUCT, LAMINATE, AND ELECTRONIC COMPONENT JSR CORPORATION (JP) 2024-01-25 US disclosed
US-7179684-B2 Microelectronic or optoelectronic package having a polybenzoxazine-based film as an underfill material INTEL CORPORATION (US) 2007-02-20 US disclosed
US-20070007692-A1 Curable compositions for advanced processes, and products made therefrom Henkel IP & Holding GmbH (DE) 2007-01-11 US disclosed
US-20070007692-A1 Curable compositions for advanced processes, and products made therefrom Henkel IP & Holding GmbH (DE) 2007-01-11 US disclosed
US-6905590-B2 Coating composition containing benzoxazine compound NIPPON PAINT CO., LTD. (JP) 2005-06-14 US disclosed
US-6558783-B1 Thermosetting polyphenylene ether resin composition, cured resin composition obtained therefrom, and laminated structure ASAHI KASEI KABUSHIKI KAISHA (JP) 2003-05-06 US disclosed
US-20030038031-A1 Coating composition containing benzoxazine compound NIPPON PAINT CO., LTD. 2003-02-27 US disclosed
EP-1247844-A2 Coating composition containing benzoxazine compounds Nippon Paint Co., Ltd. (JP) 2002-10-09 EP disclosed
EP-1063262-A1 THERMOSETTING POLYPHENYLENE ETHER RESIN COMPOSITION, CURED RESIN COMPOSITION OBTAINED THEREFROM, AND LAMINATED STRUCTURE Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-12-27 EP disclosed