Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10642813 | 0.92 | MAOA (0.51) | TSHRMAOAKDM1AMAOBCA12 | |
| SCHEMBL9778760 | 0.90 | KDM4E (0.45) | TSHRMAOAMAOBPTGS1PTGS2 | |
| SCHEMBL9778533 | 0.86 | APP (0.51) | MAOBLMNAKDM4EALDH1A1POLB | |
| SCHEMBL11086094 | 0.84 | TSHR (0.51) | TSHRMAOACA12CA1CA7 | |
| SCHEMBL29576576 | 0.84 | TSHR (0.51) | TSHRMAOACA12CA1CA7 | |
| SCHEMBL7632848 | 0.82 | TSHR (0.44) | TSHRKMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL9778604 | 0.82 | KDM4E (0.50) | MAOAKDM1AMAOBPTGS1PTGS2 | |
| SCHEMBL4825695 | 0.80 | TSHR (0.46) | TSHRMAOAKMT2AALDH1A1 | |
| SCHEMBL327430 | 0.79 | GLA (0.51) | TSHRKMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL9778743 | 0.79 | MAOA (0.53) | TSHRMAOAMAOBKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444483-B | Preparation method of 1, 3-dithiane substituted diene derivative | 兰州大学 | 2025-04-08 | — | — | CN | disclosed |
| CN-119504474-A | Preparation method of phenyl ketone amide compound | 淮北师范大学 | 2025-02-25 | — | — | CN | disclosed |
| CN-117603183-A | 1,3-dithiane modified alpha, beta-unsaturated derivative and preparation method thereof | 兰州大学 | 2024-02-27 | — | — | CN | disclosed |
| CN-117069645-A | Tryptophan and C2 alkylation modification method for tryptophan-containing polypeptide | 兰州大学 | 2023-11-17 | — | — | CN | disclosed |
| US-20230322820-A1 | BISACYL DIGERMANIUM COMPOUNDS, THEIR PREPARATION AND THEIR USE AS PHOTOINITIATOR FOR RADICAL POLYMERIZATION | EVONIK OPERATIONS GMBH (DE) | 2023-10-12 | — | — | US | disclosed |
| US-20230322820-A1 | BISACYL DIGERMANIUM COMPOUNDS, THEIR PREPARATION AND THEIR USE AS PHOTOINITIATOR FOR RADICAL POLYMERIZATION | EVONIK OPERATIONS GMBH (DE) | 2023-10-12 | — | — | US | disclosed |
| US-20230322820-A1 | BISACYL DIGERMANIUM COMPOUNDS, THEIR PREPARATION AND THEIR USE AS PHOTOINITIATOR FOR RADICAL POLYMERIZATION | EVONIK OPERATIONS GMBH (DE) | 2023-10-12 | — | — | US | disclosed |
| EP-4257592-A1 | BISACYL DIGERMANIUM COMPOUNDS, THEIR PREPARATION AND THEIR USE AS PHOTOINITIATOR FOR RADICAL POLYMERIZATION | Evonik Operations GmbH (DE) | 2023-10-11 | — | — | EP | disclosed |
| EP-4257592-A1 | BISACYL DIGERMANIUM COMPOUNDS, THEIR PREPARATION AND THEIR USE AS PHOTOINITIATOR FOR RADICAL POLYMERIZATION | Evonik Operations GmbH (DE) | 2023-10-11 | — | — | EP | disclosed |
| CN-116444483-A | Preparation method of 1,3-dithiane substituted diene derivative | 兰州大学 | 2023-07-18 | — | — | CN | disclosed |
| US-20100240748-A1 | TETRAHYDRONAPHTHALEN-2-OL DERIVATIVES | N. V. ORGANON | 2010-09-23 | — | — | US | disclosed |
| WO-2010103095-A1 | TETRAHYDRONAPHTHALEN-2-OL DERIVATIVES | N.V. ORGANON (NL) | 2010-09-16 | — | — | WO | disclosed |
| US-20080176862-A1 | Cognitive impairment, Alzheimer disease, neurodegeneration, dementia; such as 3'-(2-amino-4-(2-chloropyridin-4-yl)-1-methyl-5-oxo-4,5-dihydro-1H-imidazol-4-yl)-5-chlorobiphenyl-3-yl methanesulfonate; Beta site APP Cleaving Enzyme (BACE) inhibitors | ASTRAZENECA AB (SE) | 2008-07-24 | — | — | US | disclosed |
| US-20080176862-A1 | Cognitive impairment, Alzheimer disease, neurodegeneration, dementia; such as 3'-(2-amino-4-(2-chloropyridin-4-yl)-1-methyl-5-oxo-4,5-dihydro-1H-imidazol-4-yl)-5-chlorobiphenyl-3-yl methanesulfonate; Beta site APP Cleaving Enzyme (BACE) inhibitors | ASTRAZENECA AB (SE) | 2008-07-24 | — | — | US | disclosed |
| US-20080176862-A1 | Cognitive impairment, Alzheimer disease, neurodegeneration, dementia; such as 3'-(2-amino-4-(2-chloropyridin-4-yl)-1-methyl-5-oxo-4,5-dihydro-1H-imidazol-4-yl)-5-chlorobiphenyl-3-yl methanesulfonate; Beta site APP Cleaving Enzyme (BACE) inhibitors | ASTRAZENECA AB (SE) | 2008-07-24 | — | — | US | disclosed |
| WO-2008076046-A1 | NOVEL 2-AMINO-5, 5-DIARYL-IMIDAZOL-4-ONES | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |
| WO-2008076046-A1 | NOVEL 2-AMINO-5, 5-DIARYL-IMIDAZOL-4-ONES | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |
| JP-2000159929-A | ARYLTHIOACETAL USEFUL AS STABILIZER IN POLYMER MATERIAL | GREAT LAKES CHEM CORP | 2000-06-13 | — | — | JP | disclosed |
| EP-1004623-A1 | Aryl thioacetals useful as stabilizers in polymeric materials | GREAT LAKES CHEMICAL CORPORATION (US) | 2000-05-31 | — | — | EP | disclosed |
| US-5063197-A | Aromatic compound | MITSUBISHI PAPER MILLS LIMITED (JP) | 1991-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176862-A1 | Cognitive impairment, Alzheimer disease, neurodegeneration, dementia; such as 3'-(2-amino-4-(2-chloropyridin-4-yl)-1-methyl-5-oxo-4,5-dihydro-1H-imidazol-4-yl)-5-chlorobiphenyl-3-yl methanesulfonate; Beta site APP Cleaving Enzyme (BACE) inhibitors | BACE1, BACE2, PSEN1 | TSHR 4849/4885MAOA 1622/4885KDM1A 1537/4885 |
| US-20100240748-A1 | TETRAHYDRONAPHTHALEN-2-OL DERIVATIVES | VHL, BRCA1, TPH2 | TSHR 55/4885MAOA 234/4885KDM1A 3888/4885 |
| US-20230322820-A1 | BISACYL DIGERMANIUM COMPOUNDS, THEIR PREPARATION AND THEIR USE AS PHOTOINITIATOR FOR RADICAL POLYMERIZATION | GLRA3, GLRA2, CBR3 | TSHR 591/4885MAOA 1666/4885KDM1A 2304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.