Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Benzoate SCHEMBL2762273 | 0.86 | LMNA (0.70) | NPC1RAB9ALMNASMN1; SMN2GAA | |
| Ethyl Benzoate SCHEMBL55674 | 0.86 | LMNA (0.70) | NPC1RAB9ALMNASMN1; SMN2GAA | |
| Ethyl Benzoate SCHEMBL25388294 | 0.86 | LMNA (0.70) | NPC1RAB9ALMNASMN1; SMN2GAA | |
| Ethyl Benzoate SCHEMBL28871046 | 0.84 | LMNA (0.68) | NPC1RAB9ALMNASMN1; SMN2GAA | |
| Ethyl Benzoate SCHEMBL595705 | 0.84 | LMNA (0.68) | NPC1RAB9ALMNASMN1; SMN2GAA | |
| Ethyl Benzoate SCHEMBL29554608 | 0.84 | LMNA (0.68) | NPC1RAB9ALMNASMN1; SMN2GAA | |
| Ethyl Benzoate SCHEMBL30886688 | 0.84 | LMNA (0.68) | NPC1RAB9ALMNASMN1; SMN2GAA | |
| Ethyl Benzoate SCHEMBL10340677 | 0.84 | LMNA (0.68) | NPC1RAB9ALMNASMN1; SMN2GAA | |
| Ethyl Benzoate SCHEMBL9345283 | 0.84 | LMNA (0.68) | NPC1RAB9ALMNASMN1; SMN2GAA | |
| Ethyl Benzoate SCHEMBL1404143 | 0.84 | LMNA (0.68) | NPC1RAB9ALMNASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674943-B2 | Solid, hydrocarbon-insoluble, catalyst component containing magnesium, titanium, and halogen, and further contains an internal electron donor which does not contain a phthalate derivative, for example, ethyl (phenylacetoxy)acetate; stereospecific polymerization; highly crystalline propylene polymers | INEOS USA LLC (US) | 2010-03-09 | — | — | US | disclosed |
| US-7491781-B2 | Propylene polymer catalyst donor component | INEOS USA LLC (US) | 2009-02-17 | — | — | US | disclosed |
| US-20080214881-A1 | Propylene polymer catalyst donor component | INEOS USA LLC | 2008-09-04 | — | — | US | disclosed |
| US-20080207972-A1 | Propylene polymer catalyst donor component | INEOS USA LLC | 2008-08-28 | — | — | US | disclosed |
| US-20080194782-A1 | Propylene polymer catalyst donor component | INEOS USA LLC | 2008-08-14 | — | — | US | disclosed |
| US-20070179047-A1 | Propylene polymer catalyst donor component | INNOVENE USA (US) | 2007-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214881-A1 | Propylene polymer catalyst donor component | RAD52, NR2C2, PGR | NPC1 3789/4885RAB9A 4649/4885LMNA 4627/4885 |
| US-20080207972-A1 | Propylene polymer catalyst donor component | RAD52, NR2C2, PGR | NPC1 3789/4885RAB9A 4649/4885LMNA 4627/4885 |
| US-20080194782-A1 | Propylene polymer catalyst donor component | RAD52, NR2C2, PGR | NPC1 3789/4885RAB9A 4649/4885LMNA 4627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.