Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 11/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.32 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26169637 | 0.80 | EPHX2 (0.40) | P2RX7EPHX2NR1H4LMNA | |
| SCHEMBL18716200 | 0.80 | ALDH1A1 (0.36) | MGLL | |
| SCHEMBL12993049 | 0.80 | EPHX2 (0.46) | CDK5TAOK1CLK4EPHX2NR1H4 | |
| SCHEMBL13844973 | 0.79 | CA12 (0.35) | MGLL | |
| SCHEMBL26169644 | 0.76 | EPHX2 (0.40) | EPHX2NR1H4LMNA | |
| SCHEMBL26169654 | 0.76 | EPHX2 (0.40) | EPHX2NR1H4LMNA | |
| SCHEMBL12756281 | 0.73 | MAPK1 (0.35) | LMNAMGLL | |
| SCHEMBL26167881 | 0.71 | P2RX7 (0.40) | P2RX7EPHX2 | |
| SCHEMBL13198116 | 0.69 | KLK1 (0.32) | — | |
| SCHEMBL12137652 | 0.69 | P2RX7 (0.38) | P2RX7EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687236-B2 | Fluorescent nucleobase conjugates having anionic linkers | APPLIED BIOSYSTEMS, LLC (US) | 2010-03-30 | — | — | US | disclosed |
| US-20090092986-A1 | Fluorescent Nucleobase Conjugates Having Anionic Linkers | APPLIED BIOSYSTEMS INC. (US) | 2009-04-09 | — | — | US | disclosed |
| US-7429651-B2 | Fluorescent nucleobase conjugates having anionic linkers | APPLERA CORPORATION (US) | 2008-09-30 | — | — | US | disclosed |