Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.51 |
| ▸ | PHGDH | O43175 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12781874 | 0.83 | MAPT (0.70) | KMT2AMEN1MAPTLMNANPSR1 | |
| SCHEMBL13589640 | 0.81 | MEN1 (0.67) | KMT2AMEN1MAPTLMNANPSR1 | |
| SCHEMBL7838852 | 0.79 | MEN1 (0.60) | KMT2AMEN1MAPTLMNANPSR1 | |
| SCHEMBL3184169 | 0.78 | MEN1 (0.63) | KMT2AMEN1MAPTLMNANPSR1 | |
| SCHEMBL3180448 | 0.77 | ALDH1A1 (0.61) | KMT2AMEN1MAPTLMNANPSR1 | |
| SCHEMBL4670098 | 0.77 | USP2 (0.72) | KMT2AMEN1MAPTLMNANPSR1 | |
| SCHEMBL12282092 | 0.77 | MAPT (0.76) | KMT2AMEN1MAPTLMNANPSR1 | |
| SCHEMBL27610366 | 0.77 | MAPT (0.74) | KMT2AMEN1MAPTLMNANPSR1 | |
| SCHEMBL10100896 | 0.77 | MEN1 (0.57) | KMT2AMEN1MAPTLMNANPSR1 | |
| SCHEMBL13588798 | 0.77 | MEN1 (0.57) | KMT2AMEN1MAPTLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010025436-A2 | NITROGEN AND SULFUR-CONTAINING HETEROCYCLE DERIVATIVES | TRIAD MULTITECH PHARMACEUTICALS, INC. (US) | 2010-03-04 | — | — | WO | disclosed |