Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18509097 | 0.85 | SCN5A (0.33) | SCN5ASCN9A | |
| SCHEMBL13132283 | 0.84 | REN (0.35) | — | |
| SCHEMBL13448685 | 0.80 | SCN5A (0.33) | SCN5ASCN9A | |
| SCHEMBL18509000 | 0.76 | CYP4A11 (0.36) | — | |
| SCHEMBL13132310 | 0.69 | REN (0.35) | — | |
| SCHEMBL13132275 | 0.68 | REN (0.36) | — | |
| SCHEMBL18508757 | 0.67 | SCN5A (0.33) | SCN5ASCN9A | |
| SCHEMBL18508738 | 0.66 | SCN5A (0.44) | SCN5ASCN9A | |
| SCHEMBL13132282 | 0.65 | REN (0.38) | — | |
| SCHEMBL13132262 | 0.61 | PTGER4 (0.44) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2168952-B1 | MORPHOLINE DERIVATIVES AS RENIN INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2017-02-15 | — | — | EP | disclosed |
| EP-2168952-A1 | MORPHOLINE DERIVATIVE | Mitsubishi Tanabe Pharma Corporation (JP) | 2010-03-31 | — | — | EP | disclosed |