SCHEMBL13449161

SCHEMBL13449161

CC(C)(C)c1cc(C(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H](CCCNC(=N)N)C(=O)NCC(=O)O)cc(C(C)(C)C)c1O

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 15/20 0.46
▸ NPY1R P25929 9/20 0.46
▸ NPY5R Q15761 8/20 0.46
▸ NPY2R P49146 5/20 0.46
▸ FOLH1 Q04609 2/20 0.44
▸ KISS1R Q969F8 1/20 0.44
▸ F2 P00734 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3385091 0.92 NPY4R (0.41) NPY4RNPY1RNPY5RNPY2R
SCHEMBL3385099 0.88 CCKBR (0.39) NPY4RNPY1RNPY5RNPY2R
SCHEMBL13448796 0.88 CCKBR (0.39) NPY4RNPY1RNPY5RNPY2R
SCHEMBL13449178 0.88 CCKBR (0.39) NPY4RNPY1RNPY5RNPY2R
SCHEMBL247240 0.84 NPY4R (0.42) NPY4RNPY1RNPY5RNPY2R
SCHEMBL10024402 0.82 NPY4R (0.44) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29630450 0.81 NPY4R (0.54) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL29630348 0.81 QRFPR (0.53) NPY4RNPY1RNPY5RNPY2R
SCHEMBL13449160 0.81 NPY4R (0.60) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL29590985 0.80 QRFPR (0.56) NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2166018-A2 Antibody binding affinity ligands Novo Nordisk A/S (DK) 2010-03-24 — — EP disclosed
EP-1831243-B1 ANTIBODY BINDING AFFINITY LIGANDS NOVO NORDISK AS (DK) 2010-03-17 — — EP disclosed
US-20080311681-A1 Antibody Binding Affinity Ligands VERSAMATRIX A/S (DK) 2008-12-18 — — US disclosed
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