Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | LAP3 | P28838 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29358824 | 1.00 | ALDH1A1 (0.46) | ALDH1A1MEN1LMNAKMT2AFOLH1 | |
| SCHEMBL6447013 | 0.88 | ALDH1A1 (0.58) | ALDH1A1MEN1LMNAKMT2AFOLH1 | |
| SCHEMBL6447009 | 0.88 | ALDH1A1 (0.58) | ALDH1A1MEN1LMNAKMT2AFOLH1 | |
| SCHEMBL12228501 | 0.87 | ALDH1A1 (0.47) | ALDH1A1MEN1LMNAKMT2AFOLH1 | |
| SCHEMBL29425348 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MEN1LMNAKMT2AFOLH1 | |
| SCHEMBL13201644 | 0.84 | ENPEP (0.42) | ALDH1A1 | |
| SCHEMBL1711477 | 0.82 | ALDH1A1 (0.51) | ALDH1A1MEN1LMNAKMT2AFOLH1 | |
| SCHEMBL1711472 | 0.82 | ALDH1A1 (0.51) | ALDH1A1MEN1LMNAKMT2AFOLH1 | |
| SCHEMBL29629477 | 0.82 | ALDH1A1 (0.51) | ALDH1A1MEN1LMNAKMT2AFOLH1 | |
| SCHEMBL29531361 | 0.82 | ALDH1A1 (0.51) | ALDH1A1MEN1LMNAKMT2AFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144011-B1 | PRODRUG COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | COULTER PHARM INC (US) | 2010-03-10 | — | — | EP | disclosed |