SCHEMBL1345429

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1345818	0.90	OPRM1 (0.49)	FLT1FYNCHEK2CDK1FES
	SCHEMBL1347900	0.85	CNR1 (0.55)	OPRM1OPRD1OPRK1HDAC8CFD
	SCHEMBL1345827	0.81	CYP11B1 (0.55)	FLT1FYNCHEK2CDK1FES
	SCHEMBL1347785	0.81	FYN (0.45)	FLT1FYNCHEK2CDK1FES
	SCHEMBL12650844	0.77	HDAC1 (0.50)	FLT1FYNCHEK2CDK1FES
	SCHEMBL1345801	0.77	HDAC6 (0.43)	FLT1FYNCHEK2CDK1FES
	SCHEMBL1788221	0.77	OPRM1 (0.54)	CDC7AURKAROCK2PIM1CDK2
	SCHEMBL1347867	0.77	OPRM1 (0.62)	ROCK1OPRM1OPRD1OPRK1CNR1
	SCHEMBL3341545	0.77	OPRM1 (0.62)	ROCK1OPRM1OPRD1OPRK1CNR1
	SCHEMBL13929187	0.76	ERN1 (0.52)	FLT1FLT3CSF1RCNR1HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.