Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | SAT1 | P21673 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1427269 | 0.84 | — | — | |
| SCHEMBL395191 | 0.83 | — | — | |
| SCHEMBL5497332 | 0.83 | MEN1 (0.50) | MEN1KMT2ACYP1A2SMN1; SMN2TSHR | |
| SCHEMBL6936352 | 0.82 | SMN1; SMN2 (0.47) | MEN1KMT2ACYP1A2SMN1; SMN2DDAH1 | |
| Hydrochloric Acid SCHEMBL395610 | 0.81 | — | — | |
| SCHEMBL4094772 | 0.81 | CYP1A2 (0.54) | MEN1KMT2ACYP1A2SMN1; SMN2TSHR | |
| Bromide SCHEMBL31185235 | 0.81 | MEN1 (0.48) | MEN1KMT2ACYP1A2SMN1; SMN2TSHR | |
| SCHEMBL6935672 | 0.80 | MEN1 (0.50) | MEN1KMT2ACYP1A2SMN1; SMN2DDAH1 | |
| SCHEMBL8327575 | 0.78 | KDM4E (0.46) | MEN1KMT2ACYP1A2ALDH1A1TSHR | |
| SCHEMBL19561122 | 0.78 | PAOX (0.50) | MEN1KMT2ACYP1A2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8063104-B2 | Guanidine derivatives as inhibitors of DDAH | UCL BUSINESS PLC (GB) | 2011-11-22 | — | — | US | disclosed |