Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | ACR | P10323 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14817293 | 0.88 | LMNA (0.68) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL16604902 | 0.88 | LMNA (0.68) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL13859676 | 0.88 | LMNA (0.68) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL13422221 | 0.86 | PARP10 (0.54) | SMN1; SMN2KMT2AMAPTPRSS1ACR | |
| SCHEMBL13422349 | 0.86 | SENP1 (0.50) | LMNAKMT2AMAPTPRSS1CA1 | |
| SCHEMBL11106255 | 0.84 | LMNA (0.58) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL11100935 | 0.84 | LMNA (0.58) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL16573857 | 0.83 | CA1 (0.75) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL16751100 | 0.83 | CA1 (0.75) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL12895907 | 0.83 | CA1 (0.75) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674876-B2 | Synthesis of novel monomers containing the trifluorovinylidene group and the cyanato group and polymers thereof | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2010-03-09 | — | — | US | disclosed |