Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | ABL1 | P00519 | 4/20 | 0.54 |
| ▸ | ITK | Q08881 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | SCD | O00767 | 1/20 | 0.50 |
| ▸ | KIT | P10721 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13457261 | 0.96 | ALDH1A1 (0.57) | ALDH1A1LMNAHPGDABL1ITK | |
| SCHEMBL13457455 | 0.89 | ITK (0.56) | ALDH1A1LMNAHPGDABL1ITK | |
| SCHEMBL13457638 | 0.88 | ITK (0.57) | ALDH1A1LMNAHPGDABL1ITK | |
| SCHEMBL13457119 | 0.83 | LRRK2 (0.64) | ALDH1A1ABL1ITKNPC1RAB9A | |
| SCHEMBL13457004 | 0.81 | HTT (0.65) | ALDH1A1ABL1NPC1RAB9AMEN1 | |
| SCHEMBL13457015 | 0.80 | SCD (0.75) | ALDH1A1ABL1NPC1RAB9AMEN1 | |
| SCHEMBL13457066 | 0.79 | SCD (0.50) | ALDH1A1ABL1ITKNPC1RAB9A | |
| SCHEMBL13457268 | 0.78 | ABL1 (0.60) | ABL1ITKNPC1RAB9AMEN1 | |
| SCHEMBL13457341 | 0.78 | MAPT (0.67) | ALDH1A1LMNAHPGDABL1ITK | |
| SCHEMBL13456998 | 0.78 | NPC1 (0.71) | ALDH1A1LMNAHPGDABL1ITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024903-A1 | BENZO[d]OXAZOLES AND BENZO[d]THIAZOLES AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-03-04 | — | — | WO | disclosed |