Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.67 |
| ▸ | NPC1 | O15118 | 8/20 | 0.67 |
| ▸ | RAB9A | P51151 | 7/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | PPARG | P37231 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.60 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.60 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.60 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.60 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 6/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13456998 | 0.94 | NPC1 (0.71) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13457119 | 0.81 | LRRK2 (0.64) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4920831 | 0.80 | SCD (0.72) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13457261 | 0.79 | ALDH1A1 (0.57) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13457004 | 0.79 | HTT (0.65) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL4923421 | 0.78 | SMN1; SMN2 (0.68) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13457015 | 0.78 | SCD (0.75) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13457002 | 0.78 | ALDH1A1 (0.63) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13457414 | 0.77 | CLK4 (0.65) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13457455 | 0.77 | ITK (0.56) | NPC1RAB9AALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024903-A1 | BENZO[d]OXAZOLES AND BENZO[d]THIAZOLES AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-03-04 | — | — | WO | disclosed |