Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 10/20 | 1.00 |
| ▸ | MAOB | P27338 | 9/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.58 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SNCA | P37840 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13457653 | 0.89 | ROCK2 (1.00) | ROCK2MAOBL3MBTL1ROCK1CDC42BPA | |
| SCHEMBL13457535 | 0.87 | ROCK2 (1.00) | ROCK2MAOBROCK1CDC42BPAMAPK10 | |
| SCHEMBL13457105 | 0.81 | ROCK2 (0.80) | ROCK2ROCK1CDC42BPAMAPK10 | |
| SCHEMBL5330099 | 0.80 | L3MBTL1 (1.00) | ROCK2MAOBL3MBTL1MAPTSNCA | |
| SCHEMBL13457096 | 0.79 | ROCK2 (0.80) | ROCK2ROCK1CDC42BPAMAPK10 | |
| SCHEMBL3265554 | 0.79 | ROCK2 (0.65) | ROCK2ROCK1CDC42BPAMAPK10MAPT | |
| SCHEMBL13457365 | 0.78 | ROCK2 (0.64) | ROCK2MAOBL3MBTL1ROCK1 | |
| SCHEMBL13457565 | 0.77 | MAOB (0.63) | ROCK2MAOBL3MBTL1MAPTSNCA | |
| SCHEMBL13457083 | 0.77 | ROCK2 (0.81) | ROCK2ROCK1CDC42BPAMAPK10 | |
| SCHEMBL13457496 | 0.76 | SMN1; SMN2 (0.62) | ROCK2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024903-A1 | BENZO[d]OXAZOLES AND BENZO[d]THIAZOLES AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-03-04 | — | — | WO | disclosed |