SCHEMBL1345786

SCHEMBL1345786

c1ccc(CONc2ncnc3nc[nH]c23)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.64
TSHR P16473 3/20 0.64
MAPK1 P28482 2/20 0.64
CYP1A2 P05177 1/20 0.64
CYP2D6 P10635 1/20 0.64
CDK2 P24941 1/20 0.64
HTT P42858 5/20 0.64
NPC1 O15118 3/20 0.64
RAB9A P51151 3/20 0.64
TP53 P04637 2/20 0.64
MEN1 O00255 1/20 0.64
MAPT P10636 1/20 0.64
HPGD P15428 1/20 0.64
KMT2A Q03164 1/20 0.64
CDC7 O00311 3/20 0.62
DBF4 Q9UBU7 3/20 0.62
TAAR1 Q96RJ0 1/20 0.61
HSD17B10 Q99714 3/20 0.59
SMN1; SMN2 Q16637 2/20 0.51
BRD4 O60885 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
6-Benzylaminopurine SCHEMBL37358 0.78 LMNA (1.00) LMNATSHRMAPK1CYP1A2CYP2D6
SCHEMBL29501839 0.78 LMNA (0.57) LMNATSHRMAPK1CYP1A2CYP2D6
6-Benzylaminopurine SCHEMBL29349525 0.78 LMNA (1.00) LMNATSHRMAPK1CYP1A2CYP2D6
SCHEMBL6753015 0.78 BRD4 (0.62) LMNATSHRMAPK1CYP1A2CYP2D6
6-Benzylaminopurine SCHEMBL8378682 0.77 LMNA (0.97) LMNATSHRMAPK1CYP1A2CYP2D6
6-Benzylaminopurine SCHEMBL30241517 0.77 LMNA (0.97) LMNATSHRMAPK1CYP1A2CYP2D6
6-Benzylaminopurine SCHEMBL218733 0.77 LMNA (0.97) LMNATSHRMAPK1CYP1A2CYP2D6
6-Benzylaminopurine SCHEMBL11477809 0.77 LMNA (0.97) LMNATSHRMAPK1CYP1A2CYP2D6
SCHEMBL4924634 0.77 LMNA (0.79) LMNATSHRMAPK1CYP1A2CYP2D6
SCHEMBL1404475 0.77 CDC7 (1.00) LMNATSHRMAPK1CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4705586-B2 2011-06-22 JP claimed
US-7656523-B2 Multiplexed raman detection with filter set INTEL CORPORATION (US) 2010-02-02 US claimed
WO-2008005899-A2 MULTIPLEXED RAMAN DETECTION WITH FILTER SET INTEL CORPORATION (US) 2008-01-10 WO claimed
US-20080002198-A1 Multiplexed Raman detection with filter set INTEL CORPORATION 2008-01-03 US claimed
US-7271896-B2 Detection of biomolecules using porous biosensors and raman spectroscopy INTEL CORPORATION (US) 2007-09-18 US claimed
US-20070155020-A1 Detection of chemical analytes by array of surface enhanced Raman scattering reactions INTEL CORPORATION (US) 2007-07-05 US claimed
JP-2007518075-A 2007-07-05 JP claimed
EP-1711823-A2 DETECTION OF BIOMOLECULES USING POROUS BIOSENSORS AND RAMAN SPECTROSCOPY Intel Corporation (US) 2006-10-18 EP claimed
WO-2005090948-A2 COMPOSITE ORGANIC-INORGANIC NANOCLUSTERS INTEL CORPORATION (US) 2005-09-29 WO claimed
US-20050196876-A1 Detection of biomolecules using porous biosensors and Raman spectroscopy INTEL CORPORATION (US) 2005-09-08 US claimed
US-20050191665-A1 Composite organic-inorganic nanoclusters INTEL CORPORATION 2005-09-01 US claimed
WO-2005066612-A2 DETECTION OF BIOMOLECULES USING POROUS BIOSENSORS AND RAMAN SPECTROSCOPY INTEL CORPORATION (A DELAWARE CORPORATION) (US) 2005-07-21 WO claimed
US-20050147963-A1 Composite organic-inorganic nanoparticles and methods for use thereof INTEL CORPORATION (US) 2005-07-07 US claimed
US-20050142567-A1 Composite organic-inorganic nanoparticles and methods for use thereof INTEL CORPORATION (US) 2005-06-30 US claimed
US-9464109-B2 Method for the selective enrichment and labeling of phosphorproteins INTEL CORPORATION (US) 2016-10-11 US disclosed
US-20150031853-A1 METHOD FOR THE SELECTIVE ENRICHMENT AND LABELING OF PHOSPHORPROTEINS INTEL CORPORATION 2015-01-29 US disclosed
US-8859734-B2 Method for the selective enrichment and labeling of phosphorproteins INTEL CORPORATION (US) 2014-10-14 US disclosed
US-20050148098-A1 Methods for using raman spectroscopy to obtain a protein profile of a biological sample INTEL CORPORATION 2005-07-07 US disclosed
US-20050148100-A1 Methods and devices for using Raman-active probe constructs to assay biological samples INTEL CORPORATION (US) 2005-07-07 US disclosed
US-20050142567-A1 Composite organic-inorganic nanoparticles and methods for use thereof INTEL CORPORATION (US) 2005-06-30 US disclosed