6-Benzylaminopurine

6-Benzylaminopurine

SCHEMBL218733

Cl.c1ccc(CNc2ncnc3nc[nH]c23)cc1

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of 6-Benzylaminopurine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDR known ✓ P35968 2/20 0.70
CSF1R known ✓ P07333 2/20 0.70
JAK2 known ✓ O60674 1/20 0.70
PRKD3 known ✓ O94806 1/20 0.70
ABL1 known ✓ P00519 1/20 0.70
LCK known ✓ P06239 1/20 0.70
RET known ✓ P07949 1/20 0.70
PDGFRB known ✓ P09619 1/20 0.70
FGFR1 known ✓ P11362 1/20 0.70
FLT1 known ✓ P17948 1/20 0.70
PRKCQ known ✓ Q04759 1/20 0.70
ACVR1 known ✓ Q04771 1/20 0.70
ROCK1 known ✓ Q13464 1/20 0.70
MAPK14 known ✓ Q16539 1/20 0.70
ALK known ✓ Q9UM73 1/20 0.70
PDE4A known ✓ P27815 1/20 0.63
PDE4B known ✓ Q07343 1/20 0.63
PDE4C known ✓ Q08493 1/20 0.63
PDE4D known ✓ Q08499 1/20 0.63
LMNA P02545 5/20 0.97

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
6-Benzylaminopurine SCHEMBL30241517 1.00 LMNA (0.97) LMNATSHRMAPK1CYP1A2CYP2D6
6-Benzylaminopurine SCHEMBL29349525 0.98 LMNA (1.00) LMNATSHRMAPK1CYP1A2CYP2D6
6-Benzylaminopurine SCHEMBL27965572 0.98 LMNA (1.00) LMNATSHRMAPK1CYP1A2CYP2D6
6-Benzylaminopurine SCHEMBL37358 0.98 LMNA (1.00) LMNATSHRMAPK1CYP1A2CYP2D6
6-Benzylaminopurine SCHEMBL27886940 0.97 LMNA (0.97) LMNATSHRMAPK1CYP1A2CYP2D6
6-Benzylaminopurine SCHEMBL11477809 0.97 LMNA (0.97) LMNATSHRMAPK1CYP1A2CYP2D6
6-Benzylaminopurine SCHEMBL27946792 0.97 LMNA (0.97) LMNATSHRMAPK1CYP1A2CYP2D6
6-Benzylaminopurine SCHEMBL8378682 0.97 LMNA (0.97) LMNATSHRMAPK1CYP1A2CYP2D6
6-Benzylaminopurine SCHEMBL28068468 0.92 LMNA (0.87) LMNATSHRMAPK1CYP1A2CYP2D6
6-Benzylaminopurine SCHEMBL27898316 0.91 LMNA (0.85) LMNATSHRMAPK1CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120108431-A1 PLANT GROWTH REGULATOR ADDITIVE TAMINCO, NAAMLOZE VENNOOTSCHAP (BE) 2012-05-03 US claimed
EP-2416653-A2 PLANT GROWTH REGULATOR ADDITIVE Taminco, Naamloze Vennootschap (BE) 2012-02-15 EP claimed
WO-2010116259-A2 PLANT GROWTH REGULATOR ADDITIVE TAMINCO, NAAMLOZE VENNOOTSCHAP (BE) 2010-10-14 WO claimed
US-20070161582-A1 Pharmaceutical compositions and methods for metabolic modulation VDF FUTURECEUTICALS 2007-07-12 US claimed
EP-1718754-A1 PLANTS MODIFIED WITH MINI-CHROMOSOMES Chromatin, Inc. (US) 2006-11-08 EP claimed
WO-2005083096-A1 PLANTS MODIFIED WITH MINI-CHROMOSOMES CHROMATIN, INC. (US) 2005-09-09 WO claimed
WO-2005020892-A2 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR METABOLIC MODULATION MITOCHROMA RESEARCH, INC. (US) 2005-03-10 WO claimed
US-20250359548-A1 METHODS OF IMPROVING STRESS TOLERANCE, GROWTH AND YIELD IN PLANTS VALENT BIOSCIENCES LLC (US) 2025-11-27 US disclosed
US-12402623-B2 Methods of improving stress tolerance, growth and yield in plants VALENT BIOSCIENCES LLC (US) 2025-09-02 US disclosed
US-20240057597-A1 METHODS OF IMPROVING STRESS TOLERANCE, GROWTH AND YIELD IN PLANTS VALENT BIOSCIENCES LLC (US) 2024-02-22 US disclosed
US-11812745-B2 Method of improving stress tolerance, growth and yield in plants VALENT BIOSCIENCES LLC (US) 2023-11-14 US disclosed
EP-4106523-A1 METHODS OF IMPROVING STRESS TOLERANCE, GROWTH AND YIELD IN PLANTS Valent BioSciences LLC (US) 2022-12-28 EP disclosed
US-8729341-B2 Plants modified with mini-chromosomes UNIVERSITY OF CHICAGO (US) 2014-05-20 US disclosed
US-20090208620-A1 Alimentary Compositions and Methods For Metabolic Modulation VDF FUTURECEUTICALS, INC. (US) 2009-08-20 US disclosed
US-20090203638-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR METABOLIC MODULATION VDF FUTURECEUTICALS, INC. (US) 2009-08-13 US disclosed
US-20080060093-A1 Plants Modified With Mini-Chromosomes UNIVERSITY OF CHICAGO (US) 2008-03-06 US disclosed
US-20070184067-A1 Alimentary compositions and methods for metabolic modulation VDF FUTURECEUTICALS 2007-08-09 US disclosed
US-20070161582-A1 Pharmaceutical compositions and methods for metabolic modulation VDF FUTURECEUTICALS 2007-07-12 US disclosed
WO-2005020892-A2 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR METABOLIC MODULATION MITOCHROMA RESEARCH, INC. (US) 2005-03-10 WO disclosed
WO-2005016268-A2 ALIMENTARY COMPOSITIONS AND METHODS FOR METABOLIC MODULATION MITOCHROMA RESEARCH, INC. (US) 2005-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070161582-A1 Pharmaceutical compositions and methods for metabolic modulation GPR119, PRKAG2, PRKAG1 KDR 2702/4885CSF1R 2091/4885JAK2 1087/4885
US-20090203638-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR METABOLIC MODULATION GPR119, PRKAG2, GCKR KDR 2694/4885CSF1R 1982/4885JAK2 1064/4885
US-20120108431-A1 PLANT GROWTH REGULATOR ADDITIVE MYB, ING2, AGXT KDR 2744/4885CSF1R 2507/4885JAK2 3584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.