SCHEMBL1345840

SCHEMBL1345840

C[Si](Cl)(Cl)CCC[N+](=O)[O-]

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
TDP1 Q9NUW8 1/20 0.35
TSHR P16473 1/20 0.33
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
BLM P54132 1/20 0.31
HBB P68871 1/20 0.31
KMT2A Q03164 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1345117 0.85
SCHEMBL1345603 0.80 ALDH1A1 (0.46) ALDH1A1TDP1TSHRMEN1LMNA
SCHEMBL1346270 0.77 ALDH1A1 (0.50) ALDH1A1TDP1TSHR
SCHEMBL11516072 0.73 ALDH1A1 (0.52) ALDH1A1TDP1TSHRMEN1LMNA
SCHEMBL942102 0.73 ALDH1A1 (0.44) ALDH1A1TDP1TSHR
SCHEMBL7634648 0.70 ALDH1A1 (0.38) ALDH1A1
SCHEMBL380203 0.70 ALDH1A1 (0.46) ALDH1A1TDP1TSHRMEN1LMNA
SCHEMBL719096 0.69 ALDH1A1 (0.67) ALDH1A1TDP1TSHRMEN1LMNA
SCHEMBL705250 0.69 ALDH1A1 (0.39) ALDH1A1
SCHEMBL523832 0.69 ALDH1A1 (0.39) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8062483-B2 Separation of chlorosilanes DOW CORNING CORPORATION (US) 2011-11-22 US claimed
EP-1957504-B1 SEPARATION OF CHLOROSILANES DOW CORNING (US) 2009-09-30 EP claimed
US-20090026062-A1 Separation Of Chlorosilanes DOW CORNING CORPORATION (US) 2009-01-29 US claimed
EP-1957504-A1 SEPARATION OF CHLOROSILANES Dow Corning Corporation (US) 2008-08-20 EP claimed
WO-2007067723-A1 SEPARATION OF CHLOROSILANES DOW CORNING CORPORATION (US) 2007-06-14 WO claimed
EP-1957504-B1 SEPARATION OF CHLOROSILANES DOW CORNING (US) 2009-09-30 EP disclosed
EP-1957504-A1 SEPARATION OF CHLOROSILANES Dow Corning Corporation (US) 2008-08-20 EP disclosed
WO-2007067723-A1 SEPARATION OF CHLOROSILANES DOW CORNING CORPORATION (US) 2007-06-14 WO disclosed