Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.54 |
| ▸ | RXRB | P28702 | 3/20 | 0.54 |
| ▸ | RXRG | P48443 | 3/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31215401 | 0.86 | MRGPRX4 (0.55) | RXRARXRBRXRGMRGPRX4PTGER1 | |
| SCHEMBL849231 | 0.83 | RXRA (0.72) | RXRARXRBRXRGMRGPRX4PTGER1 | |
| SCHEMBL1347587 | 0.78 | TSHR (0.60) | RXRARXRBRXRGMRGPRX4SRD5A2 | |
| SCHEMBL312800 | 0.77 | L3MBTL1 (0.53) | RXRARXRBRXRGMRGPRX4SRD5A2 | |
| SCHEMBL24214079 | 0.75 | HTT (0.51) | RXRARXRBRXRGMRGPRX4 | |
| SCHEMBL13951676 | 0.74 | MAOB (0.77) | RXRARXRBRXRGFFAR1MAOB | |
| SCHEMBL13434198 | 0.74 | MRGPRX4 (0.49) | RXRARXRBRXRGMRGPRX4 | |
| SCHEMBL25789823 | 0.74 | PLA2G2D (0.65) | — | |
| SCHEMBL3901040 | 0.73 | MRGPRX4 (0.60) | RXRARXRBRXRGMRGPRX4 | |
| SCHEMBL29380678 | 0.73 | CA12 (0.62) | RXRARXRBRXRGMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010026095-A1 | NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-11 | — | — | WO | disclosed |