Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ACACA | Q13085 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13458891 | 0.86 | SMN1; SMN2 (0.60) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL13458754 | 0.85 | ACACA (0.50) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL13458687 | 0.85 | ACACA (0.71) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL13458951 | 0.85 | ACACA (0.71) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL12306204 | 0.83 | KDM4E (0.63) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL13458889 | 0.83 | ACACA (0.73) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL7250047 | 0.83 | ACACA (0.50) | SMN1; SMN2NPC1RAB9AKDM4EACACA | |
| SCHEMBL3704468 | 0.83 | ACACA (0.73) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL29662015 | 0.83 | ACACA (0.50) | SMN1; SMN2NPC1RAB9AKDM4EACACA | |
| SCHEMBL5632975 | 0.78 | CYP1A1 (0.79) | MEN1KMT2ASMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161272-A1 | Phenanthrolines | BASF SE (DE) | 2010-03-10 | — | — | EP | disclosed |