Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACA | Q13085 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13458670 | 0.86 | SMN1; SMN2 (0.55) | ACACASMN1; SMN2KDM4EALDH1A1AURKA | |
| SCHEMBL13458686 | 0.85 | MEN1 (0.56) | ACACASMN1; SMN2KDM4EALDH1A1AURKA | |
| SCHEMBL13458951 | 0.83 | ACACA (0.71) | ACACASMN1; SMN2KDM4EALDH1A1AURKA | |
| SCHEMBL13458687 | 0.83 | ACACA (0.71) | ACACASMN1; SMN2KDM4EALDH1A1AURKA | |
| SCHEMBL13458889 | 0.81 | ACACA (0.73) | ACACASMN1; SMN2KDM4EALDH1A1AURKA | |
| SCHEMBL3704468 | 0.81 | ACACA (0.73) | ACACASMN1; SMN2KDM4EALDH1A1AURKA | |
| SCHEMBL29662015 | 0.79 | ACACA (0.50) | ACACASMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL7250047 | 0.79 | ACACA (0.50) | ACACASMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL12112651 | 0.77 | ACACA (0.55) | ACACASMN1; SMN2KDM4EALDH1A1AURKA | |
| SCHEMBL13458898 | 0.77 | SQOR (0.41) | ACACAKDM4EALDH1A1AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161272-A1 | Phenanthrolines | BASF SE (DE) | 2010-03-10 | — | — | EP | disclosed |