SCHEMBL13458692

SCHEMBL13458692

c1ccc(-c2ccc(-c3cc(-c4ccc5ccc6ccccc6c5c4)nc4c3ccc3c(-c5ccc(-c6ccccc6)cc5)cc(-c5ccc6ccc7ccccc7c6c5)nc34)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACACA Q13085 5/20 0.43
ALDH1A1 P00352 4/20 0.43
KDM4E B2RXH2 2/20 0.43
MAPT P10636 2/20 0.43
HPGD P15428 2/20 0.43
CYP1B1 Q16678 2/20 0.41
HSD17B10 Q99714 2/20 0.41
HIF1A Q16665 1/20 0.41
CYP11B1 P15538 1/20 0.41
CYP1A1 P04798 1/20 0.41
MEN1 O00255 1/20 0.40
MPI P34949 1/20 0.40
KMT2A Q03164 1/20 0.40
TOP1 P11387 1/20 0.40
HPRT1 P00492 1/20 0.39
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
DHODH Q02127 1/20 0.38
PTGES O14684 1/20 0.38
CYP2A6 P11509 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13458896 0.94 CYP1B1 (0.44) ACACAALDH1A1KDM4EMAPTHPGD
SCHEMBL3693799 0.92 CYP1B1 (0.45) ACACAALDH1A1KDM4EMAPTHPGD
SCHEMBL13458815 0.87 CYP1A1 (0.54) ACACAALDH1A1KDM4EMAPTHPGD
SCHEMBL13458682 0.86 CYP1A1 (0.49) ACACAALDH1A1KDM4EMAPTHPGD
SCHEMBL184973 0.85 CYP1A1 (0.56) ACACAALDH1A1KDM4EMAPTHPGD
SCHEMBL29358046 0.85 CYP1A1 (0.56) ACACAALDH1A1KDM4EMAPTHPGD
SCHEMBL29373621 0.85 CYP1A1 (0.56) ACACAALDH1A1KDM4EMAPTHPGD
SCHEMBL3358457 0.85 ACACA (0.50) ACACAALDH1A1KDM4EMAPTHPGD
SCHEMBL17899330 0.85 ACACA (0.50) ACACAALDH1A1KDM4EMAPTHPGD
SCHEMBL3698074 0.85 ACACA (0.50) ACACAALDH1A1KDM4EMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2161272-A1 Phenanthrolines BASF SE (DE) 2010-03-10 EP disclosed