Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trimethylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylammonium SCHEMBL69320 | 1.00 | FFAR3 (0.32) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL4846053 | 0.94 | FFAR3 (0.36) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Ammonia Solution, Strong SCHEMBL7054400 | 0.93 | FFAR3 (0.34) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL6142286 | 0.92 | — | — | |
| SCHEMBL10663698 | 0.92 | — | — | |
| Methylamine SCHEMBL5692650 | 0.91 | FFAR3 (0.33) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Trimethylammonium SCHEMBL4972950 | 0.90 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL10893137 | 0.90 | FFAR3 (0.30) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Sulfuric Acid SCHEMBL8399982 | 0.89 | FFAR3 (0.37) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Sulfuric Acid SCHEMBL16195481 | 0.89 | FFAR3 (0.37) | FFAR3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2178498-B1 | METHOD FOR TREATING DAMAGED HAIR | PROCTER & GAMBLE (US) | 2018-04-18 | — | — | EP | claimed |
| EP-1476496-B1 | METHOD FOR CONTROLLING THE STABILITY OR THE DROPLETS SIZE OF SIMPLE WATER-IN-OIL EMULSIONS, AND STABILIZED SIMPLE WATER-IN-OIL EMULSIONS | RHODIA CHIMIE SA (FR) | 2016-07-20 | — | — | EP | claimed |
| EP-2134312-B1 | PERSONAL CARE COMPOSITIONS CONTAINING AT LEAST TWO CATIONIC POLYMERS AND AN ANIONIC SURFACTANT | PROCTER & GAMBLE (US) | 2014-10-29 | — | — | EP | claimed |
| EP-2579972-A1 | METHOD FOR PREPARING A NON-IONIC SURFACTANT STABLE PERSONAL CARE DISPERSION | The Procter and Gamble Company (US) | 2013-04-17 | — | — | EP | claimed |
| EP-2209824-B1 | HIGH DEFINITION PRINTING WITH WATERBORNE INKS ON NON-POROUS SUBSTRATES | RHODIA (US) | 2012-08-08 | — | — | EP | claimed |
| US-8025918-B2 | High definition printing with waterborne inks on non-porous substrates | RHODIA, INC. (US) | 2011-09-27 | — | — | US | claimed |
| EP-2209824-A2 | HIGH DEFINITION PRINTING WITH WATERBORNE INKS ON NON-POROUS SUBSTRATES | Rhodia, Inc. (US) | 2010-07-28 | — | — | EP | claimed |
| EP-1854843-B1 | Cosmetic composition comprising a block copolymer | RHODIA CHIMIE SA (FR) | 2009-09-09 | — | — | EP | claimed |
| WO-2009065004-A2 | HIGH DEFINITION PRINTING WITH WATERBORNE INKS ON NON-POROUS SUBSTRATES | RHODIA, INC. (US) | 2009-05-22 | — | — | WO | claimed |
| US-20090130295-A1 | High Definition Printing With Waterborne Inks on Non-Porous Substrates | RHODIA OPERATIONS (FR) | 2009-05-21 | — | — | US | claimed |
| EP-1490411-B1 | METHOD FOR CONTROLLING THE STABILITY OF EMULSIONS AND STABILIZED EMULSIONS | RHODIA CHIMIE SA (FR) | 2009-01-21 | — | — | EP | claimed |
| US-7473730-B2 | Method for depositing a polymer onto a surface by applying a composition onto said surface | RHODIA CHIMIE (FR) | 2009-01-06 | — | — | US | claimed |
| EP-1687348-B1 | COPOLYMERS COMPRISING POLYALKYLENE OXIDE GROUPS AND QUATERNARY NITROGEN ATOMS | BASF SE (DE) | 2008-11-12 | — | — | EP | claimed |
| US-20080206355-A1 | Composition comprising a particulate zinc material, a pyrithione or a polyvalent metal salt of a pyrithione and a synthetic cationic polymer | THE PROCTER & GAMBLE COMPANY | 2008-08-28 | — | — | US | claimed |
| EP-1660548-B1 | NEW COPOLYMER HAVING A CONTROLLED STRUCTURE, AND USE THEREOF | RHODIA (US) | 2008-08-27 | — | — | EP | claimed |
| EP-1453915-B1 | COSMETIC COMPOSITION COMPRISING A BLOCK COPOLYMER | RHODIA CHIMIE SA (FR) | 2007-07-04 | — | — | EP | claimed |
| EP-0995611-B1 | Ink jet recording element | EASTMAN KODAK CO (US) | 2004-04-07 | — | — | EP | claimed |
| EP-0995610-B1 | Ink jet recording element with overcoat layer | EASTMAN KODAK CO (US) | 2003-12-03 | — | — | EP | claimed |
| US-6089704-A | Overcoat for ink jet recording element | EASTMAN KODAK COMPANY (US) | 2000-07-18 | — | — | US | claimed |
| EP-0995610-A2 | Ink jet recording element with overcoat layer | EASTMAN KODAK COMPANY (US) | 2000-04-26 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080206355-A1 | Composition comprising a particulate zinc material, a pyrithione or a polyvalent metal salt of a pyrithione and a synthetic cationic polymer | SLC39A3, SLC39A14, SLC30A7 | FFAR3 1197/4885HDAC3 1674/4885HDAC1 626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.