Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Ammonia Solution, Strong. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4846053 | 0.98 | FFAR3 (0.36) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Methylamine SCHEMBL5692650 | 0.94 | FFAR3 (0.33) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Trimethylammonium SCHEMBL69320 | 0.93 | FFAR3 (0.32) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Trimethylammonium SCHEMBL1345929 | 0.93 | FFAR3 (0.32) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL10893137 | 0.90 | FFAR3 (0.30) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL6142286 | 0.88 | — | — | |
| SCHEMBL10663698 | 0.88 | — | — | |
| Ammonia Solution, Strong SCHEMBL534131 | 0.83 | — | — | |
| SCHEMBL9101444 | 0.83 | FFAR3 (0.33) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Trimethylammonium SCHEMBL4972950 | 0.82 | ALDH1A1 (0.37) | ALDH1A1CES2CES1CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003018650-A1 | USE OF AMPHOTERIC POLYMERS AS ADDITIVES PROMOTING DIRT SEPARATION FOR SURFACE CONDITIONING | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-06 | — | — | WO | disclosed |