Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 8/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 8/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2989211 | 0.87 | NPC1 (0.41) | ALDH1A1NPC1RAB9AHSD17B10SLC2A1 | |
| SCHEMBL2996049 | 0.79 | F2 (0.42) | NPC1RAB9AHSD17B10F2F10 | |
| SCHEMBL2432043 | 0.78 | EPHB3 (0.39) | ALDH1A1NPC1RAB9AHSD17B10SLC2A1 | |
| SCHEMBL9911929 | 0.73 | HSD17B10 (0.44) | ALDH1A1NPC1RAB9AHSD17B10 | |
| SCHEMBL13459295 | 0.69 | F2 (0.39) | ALDH1A1NPC1RAB9AHSD17B10F2 | |
| SCHEMBL1430562 | 0.69 | ALDH1A1 (0.69) | ALDH1A1NPC1RAB9ASLC2A1SMN1; SMN2 | |
| SCHEMBL27821938 | 0.67 | NPC1 (0.45) | ALDH1A1NPC1RAB9AHSD17B10F2 | |
| SCHEMBL16246714 | 0.66 | SLC2A1 (0.57) | ALDH1A1NPC1RAB9ASLC2A1 | |
| SCHEMBL12164434 | 0.66 | EPHB3 (0.51) | ALDH1A1NPC1RAB9ASLC2A1CSNK1D | |
| SCHEMBL15330868 | 0.65 | ALDH1A1 (0.63) | ALDH1A1NPC1RAB9ASLC2A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010030538-A2 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-03-18 | — | — | WO | disclosed |