Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13459251 | 0.79 | CRHR1 (0.58) | CRHR1LMNASMN1; SMN2APAF1NPC1 | |
| SCHEMBL13459233 | 0.67 | CRHR1 (0.40) | CRHR1SMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL3197266 | 0.62 | CRHR1 (0.47) | CRHR1MAPK1KMT2A | |
| SCHEMBL12821356 | 0.59 | ALDH1A1 (0.71) | LMNASMN1; SMN2APAF1NPC1CASP3 | |
| SCHEMBL3216688 | 0.59 | SMN1; SMN2 (0.46) | CRHR1LMNASMN1; SMN2TP53 | |
| SCHEMBL3285946 | 0.57 | KDM4E (0.47) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL11436165 | 0.57 | CYP3A4 (0.39) | ALDH1A1 | |
| SCHEMBL3288795 | 0.56 | CRHR1 (0.58) | CRHR1SMN1; SMN2 | |
| SCHEMBL3287091 | 0.56 | CRHR1 (0.41) | CRHR1SMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL13459548 | 0.56 | SMN1; SMN2 (0.42) | CRHR1SMN1; SMN2NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010032461-A1 | NITROGEN-CONTAINING FUSED RING COMPOUND | 武田薬品工業株式会社 (JP) | 2010-03-25 | — | — | WO | disclosed |