Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 10/20 | 0.65 |
| ▸ | HTR7 | P34969 | 4/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 5/20 | 0.46 |
| ▸ | HTR3B | O95264 | 5/20 | 0.46 |
| ▸ | HTR3A | P46098 | 5/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 5/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 5/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.46 |
| ▸ | HTR5A | P47898 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 4/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221254 | 0.79 | ADRB1 (1.00) | ADRB1HTR7HTR3EHTR3BHTR3A | |
| SCHEMBL24670708 | 0.79 | MEN1 (0.55) | ADRB1MAPTALDH1A1TP53HTR2A | |
| SCHEMBL29803340 | 0.79 | ADRB1 (0.54) | ADRB1MAPTALDH1A1HTR6 | |
| SCHEMBL14747891 | 0.78 | ADRB1 (0.71) | ADRB1HTR7HTR3EHTR3BHTR3A | |
| SCHEMBL13460198 | 0.77 | USP2 (0.47) | ADRB1HTR7HTR3EHTR3BHTR3A | |
| Bromide SCHEMBL9382071 | 0.77 | ADRB1 (0.69) | ADRB1HTR7HTR3EHTR3BHTR3A | |
| SCHEMBL1600023 | 0.75 | ADRB1 (0.71) | ADRB1HTR7HTR3EHTR3BHTR3A | |
| SCHEMBL20171856 | 0.75 | ADRB1 (0.71) | ADRB1HTR7HTR3EHTR3BHTR3A | |
| SCHEMBL2874530 | 0.75 | ADRB1 (0.71) | ADRB1HTR7HTR3EHTR3BHTR3A | |
| SCHEMBL1022323 | 0.75 | ADRB1 (0.71) | ADRB1HTR7HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010031707-A1 | NEUROPEPTIDE-2 RECEPTOR (Y-2R) AGONISTS AND USES THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2010-03-25 | — | — | WO | disclosed |