Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27383392 | 0.83 | ALDH1A1 (0.58) | NAMPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7869933 | 0.81 | KMT2A (0.58) | NAMPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL13460461 | 0.80 | ALDH1A1 (0.55) | NAMPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL3093740 | 0.80 | ALDH1A1 (0.55) | NAMPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL30799179 | 0.80 | ALDH1A1 (0.55) | NAMPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9940282 | 0.79 | HPGD (0.69) | ALDH1A1MEN1KMT2ALMNAGAA | |
| SCHEMBL25683364 | 0.79 | KMT2A (0.61) | NAMPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL17845335 | 0.79 | MEN1 (0.61) | NAMPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL3093727 | 0.77 | CYP2C9 (0.61) | NAMPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL5198248 | 0.76 | ALDH1A1 (0.51) | NAMPTALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024356-A1 | NOVEL HYDROXAMIC ACID DERIVATIVE HAVING NAPHTHYRIDINE-N-OXIDE | 大正製薬株式会社 (JP) | 2010-03-04 | — | — | WO | disclosed |