Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 10/20 | 0.44 |
| ▸ | PPARA | Q07869 | 6/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13460849 | 0.96 | PPARD (0.47) | PPARDPPARAPPARGTP53MAPT | |
| SCHEMBL13460876 | 0.93 | PPARD (0.45) | PPARDPPARAPPARGTP53MAPT | |
| SCHEMBL13461061 | 0.91 | TP53 (0.43) | PPARDPPARAPPARGTP53NPC1 | |
| SCHEMBL13460848 | 0.91 | PPARD (0.41) | PPARDPPARAPPARGTP53MAPT | |
| SCHEMBL13461056 | 0.90 | PPARD (0.45) | PPARDPPARAPPARGTP53ADRB1 | |
| SCHEMBL13460753 | 0.90 | PPARD (0.41) | PPARDPPARAPPARGTP53NPC1 | |
| SCHEMBL13460751 | 0.90 | TP53 (0.42) | PPARDPPARAPPARGTP53NPC1 | |
| SCHEMBL13460940 | 0.89 | PPARD (0.46) | PPARDPPARAPPARGTP53NPC1 | |
| SCHEMBL13461052 | 0.88 | PPARG (0.47) | PPARDPPARAPPARGTP53NPC1 | |
| SCHEMBL13460801 | 0.88 | TP53 (0.41) | PPARDPPARAPPARGTP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687664-B2 | Carboxylic acid derivative, a salt thereof or an ester of them, and medicament comprising it | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |