Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 9/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13461052 | 0.93 | PPARG (0.47) | PPARDPPARATP53L3MBTL1POLB | |
| SCHEMBL13460849 | 0.92 | PPARD (0.47) | PPARDPPARATP53MAPTPPARG | |
| SCHEMBL13460797 | 0.91 | PPARD (0.55) | PPARDPPARAPPARG | |
| SCHEMBL13461056 | 0.89 | PPARD (0.45) | PPARDPPARATP53PPARG | |
| SCHEMBL13460821 | 0.89 | PPARG (0.46) | PPARDPPARAL3MBTL1POLBTHRB | |
| SCHEMBL13460972 | 0.89 | PPARD (0.44) | PPARDPPARATP53L3MBTL1POLB | |
| SCHEMBL13460883 | 0.89 | PPARD (0.44) | PPARDPPARATP53MAPTPPARG | |
| SCHEMBL13461086 | 0.88 | PPARD (0.44) | PPARDPPARATP53L3MBTL1POLB | |
| SCHEMBL13460941 | 0.88 | PPARG (0.53) | PPARDPPARAPPARG | |
| SCHEMBL13460876 | 0.87 | PPARD (0.45) | PPARDPPARATP53MAPTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687664-B2 | Carboxylic acid derivative, a salt thereof or an ester of them, and medicament comprising it | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |