Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.53 |
| ▸ | PPARD | Q03181 | 7/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13461054 | 0.92 | TP53 (0.50) | PPARGPPARDPPARA | |
| SCHEMBL13460940 | 0.88 | PPARD (0.46) | PPARGPPARDPPARA | |
| SCHEMBL13460797 | 0.86 | PPARD (0.55) | PPARGPPARDPPARA | |
| SCHEMBL3418712 | 0.86 | PPARG (0.61) | PPARGPPARDPPARA | |
| SCHEMBL13460793 | 0.85 | PPARG (0.46) | PPARGPPARDPPARA | |
| SCHEMBL13460849 | 0.83 | PPARD (0.47) | PPARGPPARDPPARA | |
| SCHEMBL13461056 | 0.81 | PPARD (0.45) | PPARGPPARDPPARA | |
| SCHEMBL13460883 | 0.80 | PPARD (0.44) | PPARGPPARDPPARA | |
| SCHEMBL13461052 | 0.80 | PPARG (0.47) | PPARGPPARDPPARA | |
| SCHEMBL13460798 | 0.79 | PPARD (0.71) | PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687664-B2 | Carboxylic acid derivative, a salt thereof or an ester of them, and medicament comprising it | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |