Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 13/20 | 0.44 |
| ▸ | PPARA | Q07869 | 7/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13460904 | 0.93 | PPARD (0.46) | PPARDPPARAPPARG | |
| SCHEMBL13460779 | 0.93 | PPARD (0.50) | PPARDPPARAPPARG | |
| SCHEMBL13460924 | 0.89 | ROCK2 (0.45) | ATMPOLBTHRBRECQLTDP1 | |
| SCHEMBL13460783 | 0.89 | PPARD (0.43) | PPARDPPARAPPARG | |
| SCHEMBL13460940 | 0.89 | PPARD (0.46) | PPARDPPARAATMPPARGPOLB | |
| SCHEMBL13460785 | 0.88 | ROCK2 (0.42) | PPARDPPARAPPARG | |
| SCHEMBL3416369 | 0.87 | PPARD (0.53) | PPARDPPARAPPARGTP53 | |
| SCHEMBL13460812 | 0.87 | PPARD (0.48) | PPARDPPARAATMPPARGPOLB | |
| SCHEMBL13460794 | 0.86 | PPARD (0.46) | PPARDPPARAATMPPARGPOLB | |
| SCHEMBL13461086 | 0.84 | PPARD (0.44) | PPARDPPARAPPARGPOLBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687664-B2 | Carboxylic acid derivative, a salt thereof or an ester of them, and medicament comprising it | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |