Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.32 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13460887 | 0.89 | TP53 (0.37) | PTGESMTNR1AMTNR1BMAPTNPC1 | |
| SCHEMBL3416704 | 0.88 | PPARA (0.41) | PTGESMTNR1AMTNR1BEPHX2NR1H4 | |
| SCHEMBL13460891 | 0.88 | HPGD (0.39) | PTGESHPGDMAPTGAANPC1 | |
| SCHEMBL13460886 | 0.82 | PPARD (0.40) | MTNR1AMTNR1BEPHX2NR1H4HPGD | |
| SCHEMBL13460953 | 0.81 | PTGES (0.38) | PTGESMAPTKMT2AMCHR1MEN1 | |
| SCHEMBL13460769 | 0.81 | PPARA (0.47) | MTNR1AMTNR1BHPGDMAPTGAA | |
| SCHEMBL13460753 | 0.79 | PPARD (0.41) | MTNR1AMTNR1BEPHX2NR1H4HPGD | |
| SCHEMBL13461056 | 0.78 | PPARD (0.45) | TP53 | |
| SCHEMBL13460804 | 0.77 | SCN2A (0.39) | MTNR1AMTNR1BEPHX2NR1H4HPGD | |
| SCHEMBL3417366 | 0.77 | PPARD (0.45) | EPHX2NR1H4MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687664-B2 | Carboxylic acid derivative, a salt thereof or an ester of them, and medicament comprising it | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |