Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.33 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13461068 | 0.89 | PTGES (0.37) | TP53MAPTMTNR1AMTNR1BPTGES | |
| SCHEMBL3417366 | 0.88 | PPARD (0.45) | TP53MAPTNPC1RAB9APPARD | |
| SCHEMBL13460891 | 0.86 | HPGD (0.39) | MAPTPTGESTHRBNPC1RAB9A | |
| SCHEMBL13461061 | 0.84 | TP53 (0.43) | TP53MAPTMTNR1AMTNR1BNPC1 | |
| SCHEMBL13460849 | 0.83 | PPARD (0.47) | TP53MAPTPPARDPPARA | |
| SCHEMBL13460751 | 0.83 | TP53 (0.42) | TP53MAPTMTNR1AMTNR1BNPC1 | |
| SCHEMBL13460876 | 0.81 | PPARD (0.45) | TP53MAPTMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL13460883 | 0.81 | PPARD (0.44) | TP53MAPTNPC1PPARDPPARA | |
| SCHEMBL13460801 | 0.80 | TP53 (0.41) | TP53MAPTMTNR1AMTNR1BNPC1 | |
| SCHEMBL13460953 | 0.80 | PTGES (0.38) | MAPTPTGESERN1PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687664-B2 | Carboxylic acid derivative, a salt thereof or an ester of them, and medicament comprising it | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |