Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | POLB | P06746 | 4/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10994393 | 0.76 | NPC1 (0.67) | ALDH1A1POLBL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL246533 | 0.74 | CYP1A2 (0.51) | ALDH1A1POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL16636641 | 0.73 | SMN1; SMN2 (0.53) | ALDH1A1POLBL3MBTL1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL637663 | 0.73 | ALDH1A1 (0.52) | ALDH1A1POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL20403480 | 0.72 | GRIN2A (0.63) | ALDH1A1POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL28878659 | 0.71 | ALDH1A1 (0.49) | ALDH1A1POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL15131088 | 0.70 | POLB (0.48) | ALDH1A1POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL29963384 | 0.70 | ALDH1A1 (0.48) | ALDH1A1POLBL3MBTL1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10996612 | 0.62 | ALDH1A1 (0.44) | ALDH1A1POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL637302 | 0.62 | LMNA (0.47) | ALDH1A1POLBL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069381-A1 | GSK-3BETAINHIBITOR | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069381-A1 | GSK-3BETAINHIBITOR | GSK3B, GSK3A, GSKIP | ALDH1A1 1473/4885POLB 2392/4885L3MBTL1 1352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.