Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL636180 | 0.72 | IDO1 (0.50) | IDO1 | |
| SCHEMBL127369 | 0.71 | IDO1 (0.69) | IDO1 | |
| SCHEMBL2201278 | 0.69 | MAOA (0.37) | IDO1 | |
| SCHEMBL1145845 | 0.69 | IDO1 (0.52) | IDO1 | |
| SCHEMBL11428396 | 0.65 | SLC6A4 (0.53) | IDO1 | |
| SCHEMBL6073335 | 0.64 | IDO1 (0.52) | IDO1 | |
| SCHEMBL494668 | 0.64 | — | — | |
| SCHEMBL19914064 | 0.64 | SLC6A4 (0.47) | IDO1 | |
| SCHEMBL635341 | 0.63 | IDO1 (0.58) | IDO1 | |
| SCHEMBL441726 | 0.63 | IDO1 (0.58) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069381-A1 | GSK-3BETAINHIBITOR | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069381-A1 | GSK-3BETAINHIBITOR | GSK3B, GSK3A, GSKIP | IDO1 1290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.