Sugi Predict

Sugi Predict / Compounds / SCHEMBL134622

SCHEMBL134622

SCHEMBL134622

c1ccc(-c2c3c(c(-c4ccccc4)c4ccccc24)-c2ccc4c5c(ccc-3c25)-c2c-4c(-c3ccccc3)c3cc(-c4ccccn4)ccc3c2-c2ccccc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DHODH Q02127 1/20 0.41
▸ PDK2 Q15119 1/20 0.41
▸ PRMT5 O14744 2/20 0.40
▸ WDR77 Q9BQA1 1/20 0.40
▸ CYP2A6 P11509 1/20 0.39
▸ LMNA P02545 4/20 0.39
▸ HPGD P15428 3/20 0.39
▸ TSHR P16473 2/20 0.39
▸ HSD17B10 Q99714 2/20 0.39
▸ RAB9A P51151 2/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ NPC1 O15118 1/20 0.39
▸ CASP3 P42574 1/20 0.39
▸ SENP8 Q96LD8 1/20 0.39
▸ SENP7 Q9BQF6 1/20 0.39
▸ SENP6 Q9GZR1 1/20 0.39
▸ TLR4 O00206 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10300903 0.89 DHODH (0.46) DHODHPDK2PRMT5WDR77CYP2A6
SCHEMBL12032294 0.88 LMNA (0.42) CYP2A6LMNAHPGDTSHRHSD17B10
SCHEMBL10300931 0.88 PRMT5 (0.46) DHODHPDK2PRMT5WDR77CYP2A6
SCHEMBL12269907 0.87 PDK2 (0.36) DHODHPDK2PRMT5WDR77LMNA
SCHEMBL275991 0.86 DHODH (0.47) DHODHPDK2PRMT5WDR77CYP2A6
SCHEMBL13903066 0.85 DHODH (0.43) DHODHPDK2PRMT5WDR77CYP2A6
SCHEMBL13335817 0.85 PDK2 (0.35) DHODHPDK2PRMT5WDR77LMNA
SCHEMBL25817512 0.84 DHODH (0.47) DHODHPDK2PRMT5WDR77CYP2A6
SCHEMBL12021378 0.84 HPGD (0.39) DHODHPDK2PRMT5WDR77LMNA
SCHEMBL24565242 0.83 DHODH (0.47) DHODHPRMT5WDR77CYP2A6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9997717-B2 Organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2018-06-12 — — US disclosed
US-20160172601-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-06-16 — — US disclosed
US-20160172601-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-06-16 — — US disclosed
US-8288017-B2 Fused ring aromatic compound and organic light-emitting device using same CANON KABUSHIKI KAISHA (JP) 2012-10-16 — — US disclosed
US-8288017-B2 Fused ring aromatic compound and organic light-emitting device using same CANON KABUSHIKI KAISHA (JP) 2012-10-16 — — US disclosed
US-20120056172-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2012-03-08 — — US disclosed
US-20120056172-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2012-03-08 — — US disclosed
US-8084147-B2 Organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2011-12-27 — — US disclosed
US-8084147-B2 Organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2011-12-27 — — US disclosed
US-20110204352-A1 FUSED RING AROMATIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME CANON KABUSHIKI KAISHA (JP) 2011-08-25 — — US disclosed
US-20110204352-A1 FUSED RING AROMATIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME CANON KABUSHIKI KAISHA (JP) 2011-08-25 — — US disclosed
US-7960041-B2 Fused ring aromatic compound and organic light-emitting device using same CANON KABUSHIKI KAISHA (JP) 2011-06-14 — — US disclosed
US-7960041-B2 Fused ring aromatic compound and organic light-emitting device using same CANON KABUSHIKI KAISHA (JP) 2011-06-14 — — US disclosed
EP-2121547-B1 ORGANIC LIGHT-EMITTING DEVICE CANON KK (JP) 2011-01-12 — — EP disclosed
US-20090295279-A1 FUSED RING AROMATIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME CANON KABUSHIKI KAISHA (JP) 2009-12-03 — — US disclosed
US-20090295279-A1 FUSED RING AROMATIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME CANON KABUSHIKI KAISHA (JP) 2009-12-03 — — US disclosed
US-20090278446-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2009-11-12 — — US disclosed
US-20090278446-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2009-11-12 — — US disclosed
WO-2008111543-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2008-09-18 — — WO disclosed
WO-2008111540-A1 FUSED RING AROMATIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME CANON KABUSHIKI KAISHA (JP) 2008-09-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090295279-A1 FUSED RING AROMATIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME ARL1, TYR, OR10J3 DHODH 2329/4885PDK2 1716/4885PRMT5 1414/4885
US-20110204352-A1 FUSED RING AROMATIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME ARL1, TYR, OR10J3 DHODH 2329/4885PDK2 1716/4885PRMT5 1414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.