SCHEMBL25817512

SCHEMBL25817512

c1ccc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5ccccn5)cc4)c4cc(-c5ccccn5)ccc34)cc2)nc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.47
PRMT5 O14744 2/20 0.46
WDR77 Q9BQA1 1/20 0.46
KDM4E B2RXH2 4/20 0.45
CCR1 P32246 3/20 0.45
CCR5 P51681 3/20 0.45
CCR8 P51685 3/20 0.45
LMNA P02545 3/20 0.45
CYP1A2 P05177 2/20 0.45
METAP1 P53582 2/20 0.45
POLB P06746 1/20 0.45
BLM P54132 1/20 0.45
HIF1A Q16665 1/20 0.45
DOHH Q9BU89 1/20 0.45
P4HTM Q9NXG6 1/20 0.45
CYP2D6 P10635 1/20 0.42
CYP19A1 P11511 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
PIK3CD O00329 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL275991 0.95 DHODH (0.47) DHODHPRMT5WDR77KDM4ECCR1
SCHEMBL10300903 0.95 DHODH (0.46) DHODHPRMT5WDR77KDM4ECCR1
SCHEMBL10300931 0.93 PRMT5 (0.46) DHODHPRMT5WDR77KDM4ECCR1
SCHEMBL24565242 0.92 DHODH (0.47) DHODHPRMT5WDR77KDM4ECCR1
SCHEMBL10030023 0.92 DHODH (0.47) DHODHPRMT5WDR77KDM4ECCR1
SCHEMBL10300965 0.92 DHODH (0.47) DHODHPRMT5WDR77KDM4ECCR1
SCHEMBL10030053 0.92 DHODH (0.47) DHODHPRMT5WDR77KDM4ECCR1
SCHEMBL16512265 0.91 KDM4E (0.54) DHODHKDM4ECCR1CCR5CCR8
SCHEMBL22139307 0.90 DHODH (0.44) DHODHPRMT5WDR77KDM4ECCR1
SCHEMBL10300930 0.90 DHODH (0.44) DHODHPRMT5WDR77KDM4ECCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230189640-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-15 US disclosed
US-20230189640-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230189640-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME AOX1, EML4, L1CAM DHODH 626/4885PRMT5 4162/4885WDR77 4262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.